Type 1 and type 2 diabetes, insulin resistance, glucose metabolism, and metabolic health
294 articles
A sweeping 2025 review reveals ghrelin's roles span immunity, neuroprotection, cardiovascular health, and addiction beyond appetite.
Imaging 16 million pancreatic cells reveals macrophage-T cell interactions and beta-cell stress signatures at the earliest, preclinical stages of type 1 diabetes.
A new PTM called lysine pyruvylation links glycolytic activity directly to gene regulation, with SIRT3 acting as the eraser.
Dom D'Agostino returns to STEM-Talk to unpack 20+ new papers on ketogenic metabolic therapy for cancer, ketone supplement safety, and HBOT for TBI.
A 745-person genomic study identifies why metformin concentrations vary so widely — with ancestry-specific genetic variants playing a key role.
A randomized trial shows that extending overnight fasting by 3 hours, timed to sleep, cuts nighttime heart rate and improves glucose control.
A major review repositions type 2 diabetes as a proteinopathy, with amylin aggregation bridging metabolic decline and neurodegeneration.
A 16-week RCT finds metformin blocks exercise-induced improvements in artery and capillary function in adults at metabolic syndrome risk.
New sensor data shows type 1 diabetics on ketogenic diets experience frequent, short-lived, asymptomatic ketosis episodes — mostly harmless.
A new review maps how tirzepatide's dual GIP/GLP-1 action reshapes metabolism across the pancreas, liver, gut, heart, kidneys, and brain.
People with schizophrenia exposed to the most nighttime light face 4x higher obesity odds and 3x higher hypertension odds.
A 5-year cohort study finds that CGM-derived time in range predicts arterial stiffness changes independently of HbA1c in type 2 diabetes.
