Type 1 and type 2 diabetes, insulin resistance, glucose metabolism, and metabolic health
294 articles
A large Japanese cohort study shows polygenic risk scores predict T2D onset, yet exercise and metabolic health blunt even high genetic risk.
Longevity experts endorse CGMs for metabolic optimization, but RCT evidence in non-diabetics is still thin.
New research argues shared household metabolic factors — not just intrauterine exposure — drive MASLD risk in offspring.
Top longevity doctors endorse CGMs for healthy adults, but evidence is mixed. Here's what the 2026 device reviews reveal.
New composite biomarker combining inflammation, nutrition, and immunity markers shows promise for cardiovascular risk assessment.
Largest European study reveals widespread undiagnosed liver fibrosis, primarily linked to metabolic factors and alcohol use.
Orforglipron approved 294 days ahead of schedule for obesity treatment, marking first drug under new priority voucher system.
Deep dive into the master regulatory pathways controlling mitochondrial biogenesis, quality control, and cellular energy homeostasis through PGC-1α coordination.
Deep dive into GLP-1 receptor mechanisms, cAMP-PKA signaling cascades, and their role in metabolic health and longevity pathways.
Discover how this powerful gut hormone controls hunger, blood sugar, and may hold keys to healthy aging.
Large study of 13,706 adults finds better glucose disposal rate significantly protects against stroke, especially in middle-aged participants.
Deep dive into sirtuin enzymatic mechanisms, substrate specificity, and their role in metabolic reprogramming through NAD+-dependent deacetylation cascades.
