Oral GLP-1 Drug Crosses Blood-Brain Barrier to Reverse Alzheimer's Metabolism
A new oral GLP-1 receptor agonist penetrates the brain, restoring astrocyte-neuron metabolic crosstalk disrupted in Alzheimer's disease.
Parkinson's disease, dopamine pathways, movement disorders, and neuroprotection
137 articles
A new oral GLP-1 receptor agonist penetrates the brain, restoring astrocyte-neuron metabolic crosstalk disrupted in Alzheimer's disease.
Baylor scientists find tubulin redirects rogue brain proteins away from toxic aggregates, pointing to a novel neurodegenerative disease strategy.
A 35-year-old woman experienced reproducible dystonic episodes triggered solely by pressure on her right upper limb — a rare neurological phenomenon.
A naturally occurring fatty acid amide activates immune cells in the retina, protecting neurons and blood vessels from degenerative damage.
A completed pilot trial tests whether 2g/day of a novel carnosine formulation can restore neuromuscular function and quality of life in MS patients.
New research reveals the basal ganglia use a push-pull system to simultaneously track movement direction and count discrete actions toward a goal.
A new mechanism links mitochondrial DNA trafficking through lysosomes to gasdermin-driven pyroptosis, with Parkinson's disease genes playing a key role.
A comprehensive review reveals how immunosenescence and chronic neuroinflammation create a self-reinforcing cycle that accelerates dopaminergic neuron loss in Parkinson's disease.
Scientists found acetylcholine surges after unexpected failure, triggering behavioral flexibility — with implications for addiction and OCD.
TONTT2 tests whether erythropoietin dose and timing can be optimized to best preserve vision after traumatic optic neuropathy.
Researchers pinpoint a brainstem pathway linking vagal signals to pain suppression and mood, explaining how VNS therapy works.
A 2-year-old's puzzling eye paralysis pattern reveals an extraordinarily rare congenital wiring error in the oculomotor nerve.