Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1,805 articles
Junevity's GalNAc siRNA candidate restores healthier gene expression in diabetic mice with no safety signals, targeting cardiometabolism and neurodegeneration.
Fractyl Health's RJVA-001 aims to restore natural GLP-1 production in the pancreas via a single gene therapy intervention.
New research shows late-onset preeclampsia drives accelerated placental aging via oxidative stress, and antioxidant treatment partially reverses the damage.
Mouse study reveals a parent-of-origin effect in early embryos that overrides direct telomere inheritance and reshapes telomere length across generations.
A large mouse study finds 8-hour nightly TRF boosts healthspan in both sexes but extends lifespan significantly only in males.
A newly identified molecular complex regulates DNA repair repression, mutation accumulation, and lifespan across 92 mammalian species.
A ketone body released during exercise activates a neuroprotective pathway that combats brain aging, pointing to both exercise and supplements as tools.
A comprehensive StatPearls review covers acarbose therapy—its indications, contraindications, and role in type 2 diabetes management.
A 2025 Nature Reviews synthesis compares Mediterranean, ketogenic, fasting, and low-calorie diets for managing type 2 diabetes.
TERT, the enzyme that extends telomeres, directly fuels inflammation via the cGAS-STING immune pathway — independent of its classic role.
Go beyond the basics to understand the molecular mechanisms linking membrane lipid composition to aging — from phospholipid remodeling to lipid raft dysfunction and oxidative cascades.
From creatine synergy with exercise to CRISPR cell-killing tools, May 2026 delivered a dense wave of longevity research advances.
