Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1,829 articles
A Nature commentary argues European funders must scale up capacity to match the ambitions of scientists pushing the boundaries of health research.
Go beyond the basics and explore the four key molecular pathways — AMPK, mTOR, sirtuins, and autophagy — that translate eating less into a slower aging clock at the cellular level.
Go beyond the basics to understand how your cells detect nutrient scarcity and orchestrate autophagy through mTORC1, AMPK, and lysosomal signaling — the molecular logic behind cellular self-renewal.
Go beyond the basics and explore how hormetic stressors speak directly to your cells' longevity machinery—activating AMPK, sirtuins, and autophagy to extend healthspan.
Explore the molecular mechanisms linking telomere erosion to cellular aging — from DNA damage signaling to the senescence-associated secretory phenotype and its systemic effects.
Go beyond the basics and explore the molecular machinery behind autophagy — from the three distinct recycling pathways to the key sensors that tell your cells when to clean house.
Go beyond the basics and understand how DNA methylation patterns encode your biological age — and what drives the gap between how old you are and how old your cells behave.
Discover how simply eating less — or taking strategic breaks from eating — can activate your body's built-in longevity switches, backed by decades of research across species.
Discover how your cells recycle their own worn-out parts to stay healthy — and why this built-in cleanup system is one of the most exciting frontiers in longevity science.
Gene therapy targeting VEGFB restored heart function and reduced fibrosis in aged mice, offering new therapeutic hope.
Researchers identify lithocholic acid as a key metabolite that reproduces caloric restriction's longevity benefits across multiple species.
A new perspective outlines how stem cells, bioprinted organs, and cross-species genes could replace — not just repair — aging biology.
