Stem cell therapies, regenerative medicine, tissue engineering, and cellular reprogramming
170 articles
Radiation triggers a Ca²⁺-NFATc1-Fis1 cascade that fragments mitochondria in bone marrow stem cells, halting bone repair — and silencing Fis1 reverses it.
A comprehensive 2025 review maps the mechanisms, sources, and clinical applications of mesenchymal stem cells and their derived exosomes across cardiovascular, neurological, autoimmune, and musculoskeletal diseases.
Dive deep into partial reprogramming, niche remodeling, senolytics, and cutting-edge clinical therapies — the molecular toolkit for reversing stem cell aging.
Discover what stem cells are, the different types found in your body, and why they're essential for keeping your organs healthy as you age.
Master the cutting-edge molecular targets, clinical trial data, and emerging therapeutic strategies aimed at reversing ECM aging — from senolytic combinations to biomaterial scaffolds and epigenetic reprogramming.
Embryonic brain precursor cells grafted into adult rat striatum successfully integrate and reduce motor deficits in a Parkinson's disease model.
Go beyond the basics to understand the enzymes, signaling pathways, and cellular crosstalk that govern how your extracellular matrix ages — and what researchers are doing about it.
Discover the invisible framework that holds your body together — and why keeping it healthy is one of the most exciting frontiers in longevity science.
A comprehensive review reveals how biomaterials, stem cells, and 3D bioprinting are converging to restore damaged endometrial tissue and treat infertility.
A rigorous mechanistic deep-dive into the molecular logic of partial reprogramming — from chromatin dynamics and epigenetic clock reversal to in vivo delivery strategies, oncogenic risks, and the path to clinical translation.
MSC-derived exosomes delivered via ear injection protect vestibular hair cells, cut apoptosis, and boost autophagy better than dexamethasone.
Go beyond the basics and explore the precise molecular mechanisms by which Yamanaka factors remodel the epigenome, silence cell identity, and unlock pluripotency — with implications for partial reprogramming therapies.
