GH and IGF-1 Shape Brain Health and Drive Neuropsychiatric Disease Risk
A major review reveals how growth hormone and IGF-1 regulate cognition, mood, and neurodegeneration — with direct implications for aging brains.
562 articles in this topic
A major review reveals how growth hormone and IGF-1 regulate cognition, mood, and neurodegeneration — with direct implications for aging brains.
Plasma BDNF levels predict sarcopenia risk and detailed walking biomechanics in 646 older adults, illuminating the brain–muscle axis.
Johns Hopkins researchers reveal how TDP-43 loss accelerates toxic tau buildup, uncovering a key mechanism in Alzheimer's and related dementias.
A new index combining brain atrophy, white matter lesions, and cognition reveals who maintains brain health with age — and who doesn't.
New research reveals hippocampal theta sweeps encode goal direction during navigation, offering clues to memory and spatial planning circuits.
New research links spinal cord tau pathology to tactile deficits and cognitive impairment in Alzheimer's via disrupted CCK neurons.
A flexible 3D crystal framework selectively traps xenon over krypton using temperature and the gas itself as triggers.
A century of twin data reveals women's educational attainment became steadily more heritable as Norway expanded opportunity and gender equality.
A new 45-item standardized protocol aims to close the gap in sideline concussion evaluation during live football matches worldwide.
A brain-penetrant compound targets a key region of TDP-43, reducing motor neuron loss and extending survival in ALS mouse models.
Two-thirds of Alzheimer cases are women. New evidence shows menopause transition—not just aging—drives that risk, opening a prevention window.
A single phosphorylation site on clock protein PER2, triggered by dietary fat, controls how fast mice synchronize to seasonal light cycles.