Antidepressants Sertraline and Indatraline Trigger Cancer Cell Death via Cholesterol
Two common antidepressants cause cholesterol buildup in cancer cell lysosomes, triggering immunogenic cell death that helps immune system fight tumors.
389 articles in this topic
Two common antidepressants cause cholesterol buildup in cancer cell lysosomes, triggering immunogenic cell death that helps immune system fight tumors.
Comprehensive review reveals promising new drug targets and immunotherapy approaches for myelofibrosis beyond current JAK inhibitor limitations.
Comprehensive review reveals glioblastoma's devastating prognosis with only 5.5% five-year survival rate and key genetic markers for treatment.
International consortium achieves consensus on standardized definition and classification for osteoradionecrosis of the jaw.
New study reveals how immune cells in tumors deliver protective proteins that block a promising cancer treatment approach.
New research reveals the initial cellular changes that lead to hepatocellular carcinoma formation.
Researchers develop selective method to restore function of mutated p53 protein, potentially offering new cancer treatment strategy.
Massive study reveals cancer mutations behave differently across tissue types, challenging gene-focused treatment approaches.
ASTER 70s trial compares treatment intensities for women 70+ with genomically high-risk breast cancer to optimize outcomes while minimizing toxicity.
Novel nanoparticle combines protein degrader with light therapy to reprogram cancer metabolism and eliminate breast tumors.
Researchers use advanced cell profiling to develop personalized immune treatments for thyroid cancer patients.
New research reveals how bone marrow cells produce taurine that feeds leukemia stem cells, offering potential therapeutic targets.