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Common Numbing Cream Triggers Life-Threatening Blood Disorder in Newborns
Longevity & Aging

Common Numbing Cream Triggers Life-Threatening Blood Disorder in Newborns

A 4-week-old infant developed severe methemoglobinemia after EMLA cream was applied for circumcision, highlighting hidden dangers of topical anesthetics.

Research Paper
May 18, 2026 0
Biodegradable Mouth Patch Delivers Peptide Drugs Without Needles
Longevity & Aging

Biodegradable Mouth Patch Delivers Peptide Drugs Without Needles

ETH Zurich researchers developed an eco-friendly buccal suction patch that boosts semaglutide and bremelanotide absorption in just 10 minutes.

Research Paper
May 18, 2026 0
Scientists Challenge BPC 157 Safety Claims Citing Research Gaps and Bias
Longevity & Aging

Scientists Challenge BPC 157 Safety Claims Citing Research Gaps and Bias

Researchers critique BPC 157 peptide literature for single-center dominance, missing dose-response data, and unverified anticancer claims.

Research Paper
May 18, 2026 0
BPC 157 Defends Against Cancer and Neurodegeneration by Mastering Angiogenesis and Nitric Oxide
Longevity & Aging

BPC 157 Defends Against Cancer and Neurodegeneration by Mastering Angiogenesis and Nitric Oxide

Researchers rebut claims that BPC 157 promotes tumor growth or neurodegeneration, citing evidence it modulates—not dysregulates—angiogenesis and NO.

Research Paper
May 18, 2026 0
Epitalon Tetrapeptide Reverses Diabetic Retinopathy's Impaired Wound Healing in Lab Model
Longevity & Aging

Epitalon Tetrapeptide Reverses Diabetic Retinopathy's Impaired Wound Healing in Lab Model

The antioxidant peptide Epitalon restores wound healing in high-glucose-damaged retinal cells by curbing oxidative stress and fibrosis.

Research Paper
May 18, 2026 0
AMPK/SIRT1/PGC-1α Pathway Emerges as Master Switch for Aging and Metabolic Disease
Longevity & Aging

AMPK/SIRT1/PGC-1α Pathway Emerges as Master Switch for Aging and Metabolic Disease

A 2025 comprehensive review maps how the AMPK/SIRT1/PGC-1α axis controls energy balance and drives neurodegeneration, diabetes, and cardiovascular disease.

Research Paper
May 18, 2026 0
Albumin Therapy Does Not Cut 90-Day Death Risk in Septic Shock Patients
Longevity & Aging

Albumin Therapy Does Not Cut 90-Day Death Risk in Septic Shock Patients

A multicenter RCT of 440 patients finds albumin replacement safe but unable to significantly reduce mortality versus standard crystalloid care.

Research Paper
May 18, 2026 0
What Every ICU Doctor Must Know About Guillain-Barré Syndrome
Longevity & Aging

What Every ICU Doctor Must Know About Guillain-Barré Syndrome

A comprehensive 2025 review covers GBS diagnosis, ICU management, immunotherapy, and emerging biomarkers for intensivists.

Research Paper
May 18, 2026 0
ISTH Updates TTP Treatment Guidelines Backing Recombinant ADAMTS-13
Longevity & Aging

ISTH Updates TTP Treatment Guidelines Backing Recombinant ADAMTS-13

The 2025 ISTH guideline update elevates recombinant ADAMTS-13 as the preferred therapy for congenital TTP while maintaining prior immune TTP recommendations.

Research Paper
May 18, 2026 0
iTTP Survival Jumps From Near Zero to 93% With Modern Treatment Trio
Longevity & Aging

iTTP Survival Jumps From Near Zero to 93% With Modern Treatment Trio

A 2025 JAMA review breaks down how plasma exchange, rituximab, and caplacizumab transformed survival in this rare blood-clotting emergency.

Research Paper
May 18, 2026 0
How Premature Immune Aging Drives Rheumatoid Arthritis Onset and Severity
Longevity & Aging

How Premature Immune Aging Drives Rheumatoid Arthritis Onset and Severity

RA patients show accelerated immune aging in T cells, B cells, and myeloid cells—predating joint inflammation and directly fueling autoimmunity.

Research Paper
May 18, 2026 0
Autophagy Both Drives and Suppresses Ferroptosis Depending on Cell Context
Longevity & Aging

Autophagy Both Drives and Suppresses Ferroptosis Depending on Cell Context

New research reveals autophagy's dual role in ferroptosis—sometimes triggering cell death, sometimes preventing it—depending on iron, lipid, and radical levels.

Research Paper
May 18, 2026 0
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