6,382 articles
EASIX — calculated from creatinine, LDH, and platelets — independently predicts mortality in over 3,200 coronary artery disease patients.
A mechanosensitive ion channel fuels arteriovenous malformations in a hereditary bleeding disorder — and blocking it reduces AVM formation in mice.
A transcription factor in endothelial cells declines with age and its loss drives fibrosis, hypertrophy, and diastolic dysfunction — but restoring it reverses damage.
Adding a vascular network to stem cell-derived islet organoids dramatically improves beta-cell calcium signaling, insulin secretion, and diabetes reversal in mice.
A 2025 review from Johns Hopkins outlines how to accurately diagnose complement-mediated TMA using functional assays and systematic testing.
People with schizophrenia exposed to the most nighttime light face 4x higher obesity odds and 3x higher hypertension odds.
Spatial proteomics reveals how aging reshapes the gut's immune landscape — and points to metformin and senolytics as potential fixes.
Two large randomized trial cohorts show H. pylori infection raises colorectal cancer risk, and eradication therapy offers lasting protection.
A 5-year cohort study finds that CGM-derived time in range predicts arterial stiffness changes independently of HbA1c in type 2 diabetes.
Emerging evidence suggests GLP-1 receptor agonists like semaglutide may reduce cocaine craving and relapse by dampening dopamine signaling.
A large retrospective study finds GLP-1 receptor agonists significantly reduce AMD risk in both diabetic and obese patients.
A 10-year Korean cohort study finds GLP-1 receptor agonists don't raise psychiatric risk compared to DPP-4 inhibitors, but show modest signals vs SGLT2 inhibitors.
