5061 articles
A massive multi-omic study of 281 patients reveals that where an infection originates—lung, gut, or skin—drives distinct immune programs in sepsis.
Researchers used proteomics to split a hybrid liver disease into two distinct subtypes with starkly different survival and cirrhosis outcomes.
A comprehensive 2025 review maps the molecular and cellular mechanisms driving immune aging, from SASP to epigenetic drift.
27-Hydroxycholesterol triggers microglial senescence through iron dysregulation, and the iron chelator deferoxamine reverses the damage.
Pre-existing immune aging signatures — not just chronological age — predict who progresses to severe COVID-19, new research shows.
Transdermal alcohol monitors paired with machine learning can now detect drinking events with over 90% accuracy — a leap beyond flawed self-reports.
AML stem cells produce BHB via autonomous ketogenesis to block ferroptosis, revealing a targetable metabolic vulnerability in leukemia.
Cytosine base editing achieved 62–89% efficiency fixing a hyperinflammatory disease gene, but revealed distinct genotoxicity risks across cell types.
People with mild cognitive impairment recruit extra brain regions and show altered muscle control just to stay balanced while thinking.
FDA approval of the first T1D delay drug nearly doubled islet autoantibody testing, but critical gaps remain in screening healthy children.
A new clinical review maps both established and emerging germline genes behind pituitary adenomas, reshaping how clinicians screen and counsel patients.
Removing the pancreas and transplanting islet cells creates unique nutrition challenges that clinicians are only beginning to address systematically.
