Results for "Alpha-Ketoglutarate" in Gut Health

20 articles

Gut Metabolite Desaminotyrosine Prevents Transplant Complications While Fighting Cancer
Gut & Microbiome

Gut Metabolite Desaminotyrosine Prevents Transplant Complications While Fighting Cancer

Bacterial metabolite from flavonoids protects against graft-versus-host disease while preserving anti-cancer effects in stem cell transplants.

Research Paper
Apr 5, 2026 0
Gut Bacteria Create a Protein Modification That Damages Liver Mitochondria
Gut & Microbiome

Gut Bacteria Create a Protein Modification That Damages Liver Mitochondria

A novel gut microbiome metabolite chemically modifies liver proteins, impairing mitochondrial function and insulin signaling in obesity and fatty liver disease.

Research Paper
Jun 25, 2026 0
Tryptophan Depletion Triggers Dangerous Neutrophil Activation in Alcoholic Liver Disease
Gut & Microbiome

Tryptophan Depletion Triggers Dangerous Neutrophil Activation in Alcoholic Liver Disease

New research reveals how low tryptophan levels in portal blood create hyper-reactive immune cells that worsen liver damage in alcohol-related disease.

Research Paper
Apr 14, 2026 0
New Trial Tests High vs Gradual Nutrition in Acute Pancreatitis Recovery
Gut & Microbiome

New Trial Tests High vs Gradual Nutrition in Acute Pancreatitis Recovery

GOULASH trial compares feeding strategies for pancreatitis patients to optimize recovery outcomes.

Research Paper
Apr 8, 2026 0
Gut Metabolite Imidazole Propionate Linked to Alzheimer's Progression
Gut & Microbiome

Gut Metabolite Imidazole Propionate Linked to Alzheimer's Progression

A bacterial gut metabolite worsens Alzheimer's pathology by damaging the blood-brain barrier and promoting tau tangles.

Research Paper
Jun 27, 2026 0
Gut Metabolite TMAO Triggers Bone Cell Aging Through Inflammatory Signaling
Gut & Microbiome

Gut Metabolite TMAO Triggers Bone Cell Aging Through Inflammatory Signaling

A gut-derived compound linked to red meat consumption may accelerate bone aging by activating a key inflammatory pathway in osteoblasts.

Research Paper
Jun 29, 2026 0
Prebiotic Formula Targets Akkermansia to Reshape Gut and Body Composition
Gut & Microbiome

Prebiotic Formula Targets Akkermansia to Reshape Gut and Body Composition

A completed clinical trial tests whether a prebiotic blend can boost Akkermansia muciniphila and support weight management in metabolic syndrome.

Clinical Trial
Jun 2, 2026 0
Engineered Gut Bacteria Slash Ammonia 10-Fold and Outperform Standard Drug
Gut & Microbiome

Engineered Gut Bacteria Slash Ammonia 10-Fold and Outperform Standard Drug

Synthetic biology meets the microbiome: designer probiotics restore gut-liver-brain balance better than rifaximin in preclinical models.

Research Paper
Apr 27, 2026 0
Gut Bacteria Changes Drive Cognitive Decline in Prostate Cancer Patients on ADT
Gut & Microbiome

Gut Bacteria Changes Drive Cognitive Decline in Prostate Cancer Patients on ADT

New research reveals how androgen deprivation therapy disrupts gut microbiome and bile acids, causing memory problems through brain signaling pathways.

Research Paper
Apr 3, 2026 0
Gut Bacteria Metabolites Control Fat Storage Through Autophagy Protein Atg2
Gut & Microbiome

Gut Bacteria Metabolites Control Fat Storage Through Autophagy Protein Atg2

New research reveals how gut microbes produce fatty acids that hijack cellular cleanup systems, leading to fat accumulation and immune dysfunction.

Research Paper
Mar 28, 2026 2
Gut Bacteria Prevent Dairy Cow Ketosis Through Liver-Protective Acetate Pathway
Gut & Microbiome

Gut Bacteria Prevent Dairy Cow Ketosis Through Liver-Protective Acetate Pathway

Multi-omics study reveals how specific gut microbes produce acetate to protect liver function and prevent metabolic disorders in dairy cows.

Research Paper
Apr 5, 2026 0
Gut Bacteria Akkermansia Protects Hearts from Chemo Drug Doxorubicin Damage
Gut & Microbiome

Gut Bacteria Akkermansia Protects Hearts from Chemo Drug Doxorubicin Damage

Study shows probiotic bacteria shields heart muscle from toxic effects of cancer chemotherapy through metabolite pathway.

Research Paper
Apr 3, 2026 0
Gut Bacteria Produce Succinate That Worsens Asthma Through Protein Modification
Gut & Microbiome

Gut Bacteria Produce Succinate That Worsens Asthma Through Protein Modification

New research reveals how gut microbiota-derived succinate exacerbates allergic airway inflammation by altering lung proteins.

Research Paper
Apr 3, 2026 0
Gut Bacteria Transplants Double Cancer Treatment Success in Kidney Cancer Trial
Gut & Microbiome

Gut Bacteria Transplants Double Cancer Treatment Success in Kidney Cancer Trial

Fecal transplants from cancer survivors significantly improved treatment outcomes for metastatic kidney cancer patients.

Research Paper
Mar 29, 2026 0
AI Model Predicts Liver Cancer Treatment Success Using Hypoxia and Immune Markers
Gut & Microbiome

AI Model Predicts Liver Cancer Treatment Success Using Hypoxia and Immune Markers

New fusion model accurately predicts survival outcomes for liver cancer patients receiving TACE therapy using CT scans and biomarkers.

Research Paper
Mar 28, 2026 0
Gut Bacteria Metabolite Propionic Acid Reverses Age-Related Decline in Egg Quality
Gut & Microbiome

Gut Bacteria Metabolite Propionic Acid Reverses Age-Related Decline in Egg Quality

Study reveals how gut microbiota-derived propionic acid can restore reproductive function and reverse aging effects through gut-organ communication.

Research Paper
Mar 28, 2026 2
Gut Bacteria Compound NDGA Protects Against Age-Related Intestinal Inflammation
Gut & Microbiome

Gut Bacteria Compound NDGA Protects Against Age-Related Intestinal Inflammation

Aging reduces beneficial gut bacteria that produce NDGA, a compound that prevents inflammatory bowel disease by blocking immune cell death.

Research Paper
Mar 30, 2026 0
Gut Bacteria Enzyme Boosts IBD Drug Response Through Lactate-Histone Pathway
Gut & Microbiome

Gut Bacteria Enzyme Boosts IBD Drug Response Through Lactate-Histone Pathway

A microbial enzyme from Bifidobacterium enhances anti-TNF therapy efficacy in IBD by reshaping immune regulation via histone lactylation.

Research Paper
May 15, 2026 0
How Gut Bacteria Determine Bone Marrow Transplant Survival Odds
Gut & Microbiome

How Gut Bacteria Determine Bone Marrow Transplant Survival Odds

A landmark review reveals how microbiome disruption before and after stem cell transplants drives deadly graft-versus-host disease.

Research Paper
Jun 15, 2026 0
Gut Bacteria Drive Aging Through Toxic Metabolites That Damage Multiple Organs
Gut & Microbiome

Gut Bacteria Drive Aging Through Toxic Metabolites That Damage Multiple Organs

New research reveals how harmful gut bacterial compounds accelerate aging by disrupting metabolism across the liver, lungs, and brain.

Research Paper
Mar 28, 2026 2
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