Heart Enzyme PYGM Shields Against Heart Attack by Boosting Energy and Autophagy
A muscle enzyme that declines in heart attack patients may hold the key to preserving cardiac function after MI.
20 articles
A muscle enzyme that declines in heart attack patients may hold the key to preserving cardiac function after MI.
New research reveals how GRK2 protein clumping damages brain cells and identifies potential therapeutic targets to slow cognitive decline.
Learn what glucose and ketones in your urine actually mean for your metabolic health and diabetes risk.
Long-term follow-up shows cliramitug safely depletes cardiac amyloid with improving heart structure, function, and quality of life.
A 330-patient multicenter RCT tests whether thymosin α1 can curb immune dysregulation and organ dysfunction after acute type A aortic dissection repair.
Scientists uncover how faulty glycogen-priming proteins cause progressive cardiomyopathy, pointing toward gene therapy and autophagy as future treatments.
Akeso's AK102 faces a placebo-controlled test in high-cardiovascular-risk patients already on statins and ezetimibe.
Deleting GTPBP3 in endothelial cells blocks angiogenesis via mtROS overload — and a mitochondria-targeted antioxidant reverses the damage.
A systematic review of 2,521 patients maps how genetic architecture shapes triglyceride severity, pancreatitis risk, and liver disease burden.
Natural isoflavone prevents cardiac enlargement through novel mitochondrial protection pathway, offering new therapeutic approach.
GLP-1 drug semaglutide demonstrates potential benefits for Alzheimer's patients following major clinical trial results.
Dr. Jamnadas reveals which foods can protect against AGEs, the hidden compounds in our diet that speed up aging and disease.
Dr. Seheult explains how peaked T-waves on EKGs signal dangerous hyperkalemia and the emergency treatment that saves lives.
Dr. Jamnadas reveals how cooking methods and food choices create AGEs that damage your body and accelerate aging at the cellular level.
A major review reveals how SGLT2 inhibitors protect the heart, kidneys, and metabolism through at least seven distinct biological mechanisms.
Real-world study of 1,559 octogenarians finds SGLT2 inhibitors reduce all-cause death by 42% and heart failure rehospitalization by 31% with no increase in adverse events.
Scientists discover how an unusual gene fusion in melanoma still drives cancer growth and responds to targeted treatment.
New research reveals how low oxygen at high altitude triggers vascular damage through metabolic changes, offering therapeutic targets.
Researchers discover how cancer cells use metabolic enzyme PHGDH to evade immune detection, opening new combination therapy approaches.
Small trial explores how amiloride improves oxygen delivery to heart muscle by enhancing potassium transport in red blood cells.