Bempedoic Acid Cuts Venous Clot Risk by 42% in Statin-Intolerant Patients
A post hoc analysis of the CLEAR Outcomes trial finds bempedoic acid significantly reduces DVT and pulmonary embolism risk.
20 articles
A post hoc analysis of the CLEAR Outcomes trial finds bempedoic acid significantly reduces DVT and pulmonary embolism risk.
A Phase 2 trial tests whether a fixed-dose combination pill can safely lower LDL cholesterol in people with type 2 diabetes.
Clinical trial shows memantine reduces premature atrial contractions by 47% and prevents atrial fibrillation in heart patients.
NEJM publishes erratum for Phase 2a study of baxdrostat in primary aldosteronism treatment
Peter Attia explores a new CETP inhibitor that may reduce cardiovascular risk and protect against Alzheimer's disease in APOE4 carriers.
Novel medication lowers stubborn blood pressure by 5% and reduces kidney damage markers by 55% in patients with chronic kidney disease.
Not all fibrates work the same way โ fenofibrate uniquely reduces apoB, cutting residual cardiovascular risk beyond statins alone.
A 2025 review examines how methylene blue's nitric oxide inhibition can restore vascular tone in septic and vasoplegic shock patients.
Phase 3 trial of IBI306, a PCSK9 inhibitor, tests LDL-C reduction in Chinese adults with high cardiovascular risk on statin therapy.
Small trial explores how amiloride improves oxygen delivery to heart muscle by enhancing potassium transport in red blood cells.
Merck's CETP inhibitor anacetrapib was evaluated alongside statin therapy to assess LDL-C lowering and HDL-C raising in hypercholesterolemia patients.
A completed Phase 3 trial evaluates obicetrapib added to maximum lipid-lowering therapy in patients with familial hypercholesterolemia and ASCVD.
A phase 3 trial adding ERN/LRPT to statin therapy for dyslipidemia was terminated early, raising questions about the drug's clinical future.
A pooled analysis of 2,884 patients finds obicetrapib significantly reduces coronary events after 6 months, with striking lipid improvements.
New research examines whether proton pump inhibitors interfere with clopidogrel's protective effects against heart attacks.
The first disease-specific treatment for Barth syndrome gains FDA accelerated approval, targeting mitochondrial dysfunction to restore muscle strength.
New research reveals finerenone may reduce new-onset atrial fibrillation in heart failure patients with preserved ejection fraction.
New meta-analysis shows PCSK9 inhibitors significantly reduce cardiovascular events and major amputations in PAD patients beyond standard statin therapy.
A Phase 3 trial pits monthly lerodalcibep against evolocumab in homozygous familial hypercholesterolemia patients over 24 weeks.
Isolinderalactone from Lindera aggregata root reduces atherosclerotic plaques by targeting key inflammatory pathways in immune cells.