Bempedoic Acid Cuts Venous Clot Risk by 42% in Statin-Intolerant Patients
A post hoc analysis of the CLEAR Outcomes trial finds bempedoic acid significantly reduces DVT and pulmonary embolism risk.
20 articles
A post hoc analysis of the CLEAR Outcomes trial finds bempedoic acid significantly reduces DVT and pulmonary embolism risk.
New guidance suggests mothers taking bempedoic acid for cholesterol need not stop breastfeeding, though caution is advised for newborns.
A Phase 2 trial tests whether a fixed-dose combination pill can safely lower LDL cholesterol in people with type 2 diabetes.
New research reveals how the cholesterol medication bempedoic acid directly activates PPARα, boosting fat metabolism beyond its known effects.
Beta-hydroxybutyrate restores AMPA receptor function and prevents memory loss triggered by saturated fat-rich diets in mice.
A naturally occurring fatty acid amide activates immune cells in the retina, protecting neurons and blood vessels from degenerative damage.
A phase 2/3 trial of the BACE inhibitor atabecestat in amyloid-positive asymptomatic adults was terminated before completion, raising questions about this drug class.
Baxdrostat blocks aldosterone production directly, cutting systolic BP by ~15 mmHg in resistant hypertension patients who failed other drugs.
Baxdrostat becomes the first-in-class aldosterone synthase inhibitor approved to treat resistant hypertension alongside existing drugs.
A natural alkaloid from traditional Chinese medicine activates a key bile acid receptor to restore intestinal balance and reduce colitis inflammation.
A comprehensive review argues that BPC 157's effects on angiogenesis and nitric oxide are therapeutic assets, not risks, with anti-tumor and neuroprotective evidence.
A traditional Chinese herbal formula improves cognition and cerebrovascular health in Alzheimer's mice by activating the LKB1-AMPK-SIRT1 autophagy cascade.
Researchers rebut claims that BPC 157 promotes tumor growth or neurodegeneration, citing evidence it modulates—not dysregulates—angiogenesis and NO.
AstraZeneca's BAXFENDY cuts systolic blood pressure by nearly 10 mmHg beyond placebo in adults whose BP wasn't controlled by other drugs.
FDA-approved methylene blue reduced delirium-like behavior in surgical mice by suppressing neuroinflammation and repairing the blood-brain barrier.
Combining two traditional herbal compounds fixes a dangerous liver toxicity problem while making colitis treatment significantly more effective.
Modified antioxidant shows promise for preventing diabetic retinopathy and macular degeneration by boosting cellular protection.
Phase 1b trial tests escalating doses of experimental Alzheimer's treatment BMS-984923 for safety and tolerability in older adults.
A comprehensive review reveals methylene blue's expanding role from toxicology emergencies to perioperative care, neurology, and oncology.
Probucol, a discontinued cholesterol medication, may boost brain-protective proteins in older adults at risk for dementia.