20 articles
AstraZeneca's baxdrostat wins FDA approval for hypertension, offering a novel mechanism for patients uncontrolled on existing therapies.
Breakthrough prodrug technology enables oral delivery of allopregnanolone, showing promise for treating anxiety and mood disorders.
Researchers found that inhibiting LSD1 enzyme increases SEC23A protein levels, potentially treating congenital anemia.
A new wave of antidepressants is targeting patients who don't respond to standard treatments, with implications for brain health and longevity.
BIIB080 failed its primary endpoint in Phase 2, yet Biogen sees potential signals worth pursuing in the fight against Alzheimer's tau tangles.
ProcyanidinC1, a natural senolytic, selectively eliminates senescent cells in diabetic skin, dramatically improving wound healing in mouse models.
Researchers used AI screening to identify bavisant, a histamine receptor drug, as a potential therapy to repair nerve damage in MS.
A Phase 2 trial evaluates MBA-P01, a novel botulinum toxin A, for safety and optimal dosing in treating frown lines.
Novel p75 neurotrophin receptor fusion protein reduces knee pain by up to 43% compared to placebo in 518-patient randomized trial.
A novel anti-swelling hydrogel loaded with dasatinib, quercetin, and nucleus pulposus exosomes clears senescent cells and restores disc integrity in rats and goats.
Adding methylene blue to ropivacaine in a serratus anterior plane block significantly prolongs pain relief up to 72 hours post-op.
Novel iodide-enhanced hydrogel penetrates gum pockets to eliminate harmful bacteria while protecting regenerative stem cells.
MSC-derived exosomes delivered via ear injection protect vestibular hair cells, cut apoptosis, and boost autophagy better than dexamethasone.
Researchers found a way to rejuvenate blood stem cells by targeting branched-chain amino acid pathways, potentially extending healthspan.
Scientists engineer high-PS procoagulant platelets that outperform thrombin and commercial hemostatic agents, even in antiplatelet-treated patients.
Comprehensive review examines peptides like BPC-157 and TB-500 for wound healing, muscle repair, and recovery optimization in orthopedic medicine.
New comprehensive review questions effectiveness of amyloid-targeting Alzheimer's drugs, igniting debate over treatment approach.
Novel nanoparticle therapy converts inflammatory macrophages into healing cells that deliver healthy mitochondria to damaged spinal discs.
Explore the molecular mechanisms of cellular senescence and how p16/p21 pathways drive SASP production, plus cutting-edge senolytic drug targets.
Cytosine base editing achieved 62–89% efficiency fixing a hyperinflammatory disease gene, but revealed distinct genotoxicity risks across cell types.
