Bempedoic Acid Cuts Venous Clot Risk by 42% in Statin-Intolerant Patients
A post hoc analysis of the CLEAR Outcomes trial finds bempedoic acid significantly reduces DVT and pulmonary embolism risk.
20 articles
A post hoc analysis of the CLEAR Outcomes trial finds bempedoic acid significantly reduces DVT and pulmonary embolism risk.
New guidance suggests mothers taking bempedoic acid for cholesterol need not stop breastfeeding, though caution is advised for newborns.
New research reveals how the cholesterol medication bempedoic acid directly activates PPARα, boosting fat metabolism beyond its known effects.
Beta-hydroxybutyrate restores AMPA receptor function and prevents memory loss triggered by saturated fat-rich diets in mice.
A naturally occurring fatty acid amide activates immune cells in the retina, protecting neurons and blood vessels from degenerative damage.
A natural alkaloid from traditional Chinese medicine activates a key bile acid receptor to restore intestinal balance and reduce colitis inflammation.
A comprehensive review argues that BPC 157's effects on angiogenesis and nitric oxide are therapeutic assets, not risks, with anti-tumor and neuroprotective evidence.
A traditional Chinese herbal formula improves cognition and cerebrovascular health in Alzheimer's mice by activating the LKB1-AMPK-SIRT1 autophagy cascade.
Researchers rebut claims that BPC 157 promotes tumor growth or neurodegeneration, citing evidence it modulates—not dysregulates—angiogenesis and NO.
FDA-approved methylene blue reduced delirium-like behavior in surgical mice by suppressing neuroinflammation and repairing the blood-brain barrier.
Combining two traditional herbal compounds fixes a dangerous liver toxicity problem while making colitis treatment significantly more effective.
Modified antioxidant shows promise for preventing diabetic retinopathy and macular degeneration by boosting cellular protection.
A comprehensive review reveals methylene blue's expanding role from toxicology emergencies to perioperative care, neurology, and oncology.
NEJM publishes erratum for Phase 2a study of baxdrostat in primary aldosteronism treatment
A bile acid found in blood predicts and treats obesity-induced endothelial dysfunction through a newly discovered FXR-ATF4 metabolic axis.
A stable gastric peptide called BPC 157 may offer bidirectional vascular protection, countering both hemorrhage and thrombosis without disrupting coagulation.
A new rodent study finds that beta-hydroxybutyrate salt reduces alcohol consumption in both sexes and alters dopamine signaling in the brain's reward center.
Buddleoside activates AMPK, suppresses MTORC1, and restores autophagy to combat nonalcoholic steatohepatitis in mice.
Commentary examines the therapeutic potential of BPC-157, a natural 15-amino acid peptide with remarkable cytoprotective properties.
Reverse network pharmacology pinpoints berberine as a promising treatment for CKM syndrome, validated in a novel mouse model combining metabolic and cardiac stress.