20 articles
Master the cutting-edge molecular targets, clinical trial data, and emerging therapeutic strategies aimed at reversing ECM aging — from senolytic combinations to biomaterial scaffolds and epigenetic reprogramming.
A flexible PEMF coil patch delivers targeted electromagnetic stimulation to skin wounds, offering a tunable, non-invasive approach to chronic wound repair.
Go beyond the basics to understand the enzymes, signaling pathways, and cellular crosstalk that govern how your extracellular matrix ages — and what researchers are doing about it.
A novel anti-swelling hydrogel loaded with dasatinib, quercetin, and nucleus pulposus exosomes clears senescent cells and restores disc integrity in rats and goats.
Researchers developed a new method to create aligned fibers from tendon tissue that maintain natural proteins and support cell growth.
A new prime editing approach gives scientists precise genetic control over filamentous fungi, opening the door to novel bioactive compounds.
A biodegradable microneedle stent achieves sutureless intestinal anastomosis while releasing anti-inflammatory drugs triggered by local inflammation.
Discover the invisible framework that holds your body together — and why keeping it healthy is one of the most exciting frontiers in longevity science.
Injectable hydrogel from traditional Chinese herbs shows superior wound repair by regulating immune response and promoting tissue regeneration.
A pharmacological cocktail transiently activates reprogramming genes in senescent endothelial cells, restoring function and improving blood flow in aged mice.
Radiation triggers a Ca²⁺-NFATc1-Fis1 cascade that fragments mitochondria in bone marrow stem cells, halting bone repair — and silencing Fis1 reverses it.
New research reveals how stretching forces activate stem cells and immune cells to rebuild facial bone structure through collagen remodeling.
A preclinical rat study finds pulsed electromagnetic field therapy applied remotely cuts fracture healing time from 30 to 23 days and eliminates post-surgical abscesses.
A Phase 2 trial evaluates MBA-P01, a novel botulinum toxin A, for safety and optimal dosing in treating frown lines.
New combination therapy using stem cell exosomes and spirulina-based hydrogel shows promise for treating hard-to-heal diabetic wounds.
Three days of GDF11 infusion post-injury preserved pericytes, protected the blood-spinal cord barrier, and improved functional recovery in mice.
A 12-month RCT compares three scaffold types and two EDTA concentrations for regenerating necrotic immature permanent teeth.
Epicrispr's GEMS platform silences disease genes epigenetically — reversibly and safely — with a single viral vector, targeting FSHD and beyond.
Scientists created enhanced stem cell-derived particles that promote bone regeneration and reduce inflammation in periodontal disease.
Novel nanoparticle therapy converts inflammatory macrophages into healing cells that deliver healthy mitochondria to damaged spinal discs.
