20 articles
Researchers propose a unified model classifying cancer-associated fibroblasts by molecular phenotype and spatial location to guide precision therapy.
Expert reviews compare leading senolytic and NAD+ supplement brands on ingredients, evidence quality, and value.
Expert reviews rank fisetin and quercetin as top senolytics, with spermidine and resveratrol as supporting players in longevity supplement stacks.
A new Cell Metabolism review from NIH identifies how ECM stiffening, poor blood flow, and mitochondrial failure lock tissues into accelerating decline.
A product review breaks down the evidence tiers for four popular longevity supplements and rates the best commercial stacks.
A meta-analysis of 8 studies finds intermittent fasting significantly reduces liver fat and improves key metabolic markers in MASLD patients.
A new review argues that combining GLP-1 receptor agonists with structured exercise and dietary support preserves muscle and delivers lasting fat loss.
A sweeping review organizes 20 years of anti-aging pharmacology into three intervention axes and ranks the top compounds by research impact.
A new review reframes magnesium as a master regulator of mitochondrial energy, metabolic disease, and biological aging.
Bacteriophages transferred during FMT may drive horizontal gene transfer, altering microbial function and antibiotic resistance in ways science has largely ignored.
Researchers outline innovative approaches to speed up drug development for age-related diseases and longevity interventions.
A Cochrane meta-analysis of 8 RCTs finds most pharmacological treatments fail to improve ataxia scores, though upper limb dexterity may benefit.
A new narrative review finds IF activates powerful antioxidant pathways, but warns that clinical proof in humans remains thin and short-term.
A meta-analysis of 30 RCTs finds plyometric training delivers significant gains across sprinting, jumping, and endurance metrics in track and field athletes.
A comparative review of NMN and NR supplements weighs tissue targeting, clinical evidence, and top-rated products for NAD+ optimization.
New expert reviews compare NMN and NR head-to-head, ranking top products by purity, absorption, and clinical evidence.
A new review identifies PRMT enzymes as master regulators linking mitochondrial stress to sarcopenia and neuromuscular decline.
Senescent macrophages and cell death pathways fuel atherosclerosis — and new drug targets may finally interrupt the cycle.
Independent testing reveals rampant quality failures in NMN, NR, and NAD+ supplements. Know what to look for before buying.
A new review maps the structural and functional changes that help the bowel compensate after resection, and highlights where knowledge gaps remain.
