Gut Bacteria Transplants Boost Antidepressant Effects in Clinical Trial
A double-blind RCT finds FMT capsules added to escitalopram reduce depression scores faster via bile acid and anti-inflammatory pathways.
20 articles
A double-blind RCT finds FMT capsules added to escitalopram reduce depression scores faster via bile acid and anti-inflammatory pathways.
Combined therapy restored gut health in patients who failed conventional treatments, offering new hope for refractory IBD cases.
Researchers identify a gut-microbe-driven pathway linking IBS-D and insulin resistance, with oleoylethanolamide as a key therapeutic molecule.
Study shows fasting improves cognitive performance in obesity by modifying gut bacteria and enhancing brain immune cells.
Engineered cerium-peptide microspheres show 76% reduction in IBD symptoms and 66% decrease in fibrosis markers in mouse studies.
New research reveals how microbiota-produced SCFAs directly block Candida albicans growth, pointing to prebiotic therapies for immunocompromised patients.
New research shows this beneficial gut microbe blocks obesity and improves metabolism through nicotinamide riboside production.
A common oat fiber supercharges anti-PD-1 checkpoint therapy by expanding a key gut microbe that produces immune-activating metabolites.
Fecal microbiota transplants dramatically improved immune checkpoint inhibitor response rates in lung cancer and melanoma patients.
New research shows how a specific gut bacteria enhances anti-PD-1 therapy effectiveness in hard-to-treat colorectal cancers.
A microbiota-derived short-chain fatty acid stops Candida colonization by acidifying fungal cells โ a finding with major implications for immunocompromised patients.
New research reveals how prebiotic inulin reprograms intestinal cells by creating low-oxygen conditions that activate growth signals.
New research reveals how specific gut bacteria can program neutrophils to become cancer-fighting allies in colorectal tumors.
A stem cell intestine model screened 3,500 compounds and flagged glycyrrhizin from black licorice as a top anti-inflammatory candidate for IBD.
A microbial enzyme from Bifidobacterium enhances anti-TNF therapy efficacy in IBD by reshaping immune regulation via histone lactylation.
6-methoxykaempferol from sweet cherries restored immune function by 43% and improved beneficial gut bacteria in immunocompromised mice.
New research shows how beneficial gut bacteria process plant sugars, revealing pathways that could optimize digestive health.
Bacterial metabolite from flavonoids protects against graft-versus-host disease while preserving anti-cancer effects in stem cell transplants.
New research reveals that inulin fiber can suppress immune defenses against parasites through direct effects on gut immunity.
New research reveals diagnostic challenges in identifying fatty liver disease in lean individuals using current screening tools.