Urine Test May Soon Track Senescent Cells in Cancer and Fibrosis
Cambridge scientists engineer a nanoprobe that detects therapy-induced senescence non-invasively through a simple urine colorimetric test.
20 articles
Cambridge scientists engineer a nanoprobe that detects therapy-induced senescence non-invasively through a simple urine colorimetric test.
New research reveals young and elderly cervical cancer patients have completely different molecular signatures requiring age-specific treatments.
Large study reveals cancer survivors have higher biological age than cancer-free individuals, with strongest mortality predictions from epigenetic clocks.
Study identifies blood markers that distinguish long-term survivors from short-term survivors in brain cancer treatment.
A major review reveals how inflammaging and immunosenescence synergistically drive colorectal cancer in older adults, reshaping the tumor microenvironment.
Scientists identify protein and metabolic markers in blood that can catch lung cancer in early stages when treatment is most effective.
Specific mutational signatures accumulate linearly with age in normal tissues, offering a new window into why cancer risk rises exponentially as we get older.
New research reveals how a metabolic enzyme fuels hepatocellular carcinoma progression through altered lipid synthesis pathways.
New research reveals senescent cells have both harmful and protective roles, pushing anti-aging science toward targeted removal strategies.
A growth factor called GDF11 reprograms pro-tumor macrophages by rewiring their metabolism, suppressing hepatocellular carcinoma growth.
Scientists develop advanced drug delivery methods to detect and eliminate harmful senescent tumor cells that promote cancer spread.
A French trial investigated whether circulating immune cell profiles, specifically CD226 expression, could predict who responds to Atezolizumab/Bevacizumab in advanced HCC.
New liquid biopsy combining DNA methylation and protein markers shows promise for early multi-cancer detection across nine major cancer types.
New fusion model combines hypoxia and immune markers to predict hepatocellular carcinoma treatment success non-invasively.
New technique uses cerebrospinal fluid to decode methylation signatures in children's brain tumors, potentially improving diagnosis.
New liquid biopsy using exosomes could revolutionize screening for colorectal cancer in people under 50, when traditional screening isn't recommended.
A comprehensive review reveals how the senescence secretome suppresses tumors early but drives progression, resistance, and metastasis chronically.
New research reveals how a specific protein causes anemia in myelodysplastic syndromes and predicts treatment response.
New research reveals how ฮฑ-ketoglutarate regulates AMPK synthesis, offering potential cancer therapy targets through energy stress.
Researchers used advanced genetic analysis to find LGALS9 and SELL genes causally linked to aggressive brain tumors, revealing new treatment targets.