Gut Bacteria Compound NDGA Protects Against Age-Related Intestinal Inflammation
Aging reduces beneficial gut bacteria that produce NDGA, a compound that prevents inflammatory bowel disease by blocking immune cell death.
20 articles
Aging reduces beneficial gut bacteria that produce NDGA, a compound that prevents inflammatory bowel disease by blocking immune cell death.
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Aged mouse colons get stuck in a fetal-like repair mode that makes them hypersensitive to immune attack, derailing gut healing after injury.
Small study tests synbiotic supplements to combat age-related immune decline in healthy elderly adults.
Researchers identified six blood metabolites from gut bacteria that can predict early cognitive decline with 79% accuracy.
A new review maps the bidirectional crosstalk between gut microbiota and cellular senescence driving multi-organ degeneration.
University study tests whether combining probiotics with prebiotics can restore healthy gut bacteria and immune function in people over 65.
Age-related shifts in intestinal T cell populations may silently erode gut barrier function, accelerating the chronic inflammation that drives aging diseases.
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First study to quantify food additives in Crohn's patients reveals higher sweetener levels and altered emulsifier metabolism tied to disease severity.
Analysis of 10,878 samples across 27 countries reveals how gut bacteria patterns vary by geography and age, with implications for longevity.
New research reveals how gut microbiome changes with aging contribute to macular degeneration and potential therapeutic approaches.
New research reveals how gut microbiota changes drug processing with age, offering insights for personalized elderly medication.

Gut bacteria change with age, impacting energy and cognitive function. Learn evidence-based ways to support your microbiome.
New research reveals how gut-derived postbiotics could combat brain inflammation and preserve cognitive function as we age.
New research reveals how harmful gut bacterial compounds accelerate aging by disrupting metabolism across the liver, lungs, and brain.
New research reveals how gut bacteria and immune aging create a vicious cycle that accelerates inflammaging and offers intervention targets.
A newly identified microRNA disrupts Paneth cell function in aging intestines, exposing older patients to life-threatening gut complications.
A primate single-nucleus study identifies NCoR1 decline as a conserved gut aging mechanism โ and shows metformin can restore it.
Aging disrupts gut microbiota and mTOR signaling, crippling vaccine responses โ but targeted interventions may reverse this.