20 articles
Scientists uncover how faulty glycogen-priming proteins cause progressive cardiomyopathy, pointing toward gene therapy and autophagy as future treatments.
Dr. Jamnadas reveals how cooking methods and food choices create AGEs that damage your body and accelerate aging at the cellular level.
Dr. Jamnadas reveals which foods can protect against AGEs, the hidden compounds in our diet that speed up aging and disease.
New biomarker combining inflammation and glucose metabolism predicts stroke risk better than single measurements in middle-aged adults.
New biomarker soluble endoglin shows promise for early detection of cardiovascular and metabolic disorders in blood tests.
Mendelian randomization links circulating inflammatory proteins to retinal microvascular changes, heart disease risk, and lifespan — establishing causal direction.
Scientists identify GSDME as a master switch driving abdominal aortic aneurysms through vascular aging, opening new treatment paths.
New biomarker could identify dementia risk decades before symptoms appear, enabling earlier intervention strategies.
Advanced spatial mapping shows vascular regions drive cardiac aging through inflammation and senescence accumulation.
New composite index combining triglyceride-glucose levels with frailty scores dramatically improves cardiovascular risk prediction in older adults.
A comprehensive review reveals how inflammaging—the fusion of aging and inflammation—fuels cardiovascular disease through senescence, mitochondrial dysfunction, and gut dysbiosis.
A 2025 review maps the molecular mechanisms driving cardiovascular aging—from inflammaging to ECM remodeling—and outlines emerging therapies.
Chinese study of 4,157 adults finds cumulative CTI index outperforms single measurements for cardiovascular risk prediction.
New research shows GDF11, an anti-aging protein, prevents dangerous calcium buildup in arteries by suppressing inflammatory pathways.
New research identifies unique molecular signatures in gut lymph and blood that could transform digestive health monitoring.
Scientists map a precise molecular chain linking falling NAD levels to lysosomal dysfunction, cardiolipin loss, and age-related heart failure — and show NAD restoration can reverse it.
CTI index combining inflammation and insulin resistance shows 111% higher death risk in 5,847 Chinese adults.
A novel CTSL–Notch1–CUX1 pathway drives endothelial senescence and atherosclerotic plaque buildup, revealing fresh drug targets.
New research reveals how GRK2 protein clumping damages brain cells and identifies potential therapeutic targets to slow cognitive decline.
A proteomics screen of 2,920 plasma proteins identifies a 17-protein score that lifts heart failure prediction accuracy to 0.833 C-index in type 2 diabetes patients.
