20 articles
Go beyond inflammaging basics to understand how aging reshapes immune cell populations, triggers the SASP, and locks the body into a state of chronic low-grade inflammation at the molecular level.
A mechanistic deep-dive into cutting-edge anti-inflammaging interventions — from senolytic pharmacology and precision cytokine targeting to partial reprogramming strategies that aim to restore youthful immune homeostasis.
Senescent T cells fuel psoriasis, eczema, and rosacea through toxic secretions. New therapies may finally break the cycle.
A multi-biomarker study finds pwMS show accelerated thymic involution, senescent T cell expansion, and neuroinflammation linked to aging.
BNT162b2 mRNA vaccine induces special immune cells that protect against severe illness and may slow aging-related decline.
New research reveals the precise timing signals that determine whether immune cells become immediate fighters or memory guardians.
New research reveals how IL-2 signaling generates special B cells that produce anti-inflammatory compounds, potentially slowing aging processes.
Stanford researchers used modified immune proteins to enhance neurogenesis and cognitive function in aged mouse brains.
New research reveals how our antibody responses against harmful bacteria mature and strengthen through repeated exposure over time.
Cancer immunotherapy drugs may enhance the body's natural healing processes by boosting regenerative immune responses.
Mice lacking the PERP apoptosis gene develop faulty thymic immune screening, accumulating self-reactive T-cells that trigger arthritis as they age.
Researchers identify how TSLP protein creates regulatory T cells that suppress immune responses in melanoma.
Researchers modified red blood cells to teach the immune system tolerance, potentially ending need for harsh immunosuppressive drugs.
A published correction updates the April 2026 Aging Cell paper identifying a senescence-driven, immunomodulatory subtype of endometriosis.
Scientists discover transitional dendritic cells that regulate immune responses, offering new targets for cancer therapy.
New research reveals how SIRT2 regulates T cell responses, potentially improving cancer immunotherapy and immune function.
Scientists discover how immune cells work together in unexpected ways, opening new paths for cancer therapy and transplant success.
Early influenza infections leave a lasting immunological imprint that determines how your immune system responds to entirely different flu strains later in life.
A major review in Nature Medicine explores how CAR cell therapies may achieve deep immune 'reset' in autoimmune diseases by depleting pathogenic B cells.
Breakthrough study shows CAR T-cell therapy normalizes neutrophil function in lupus, offering new hope for autoimmune treatment.
