20 articles
Scientists discover how to enhance cancer immunotherapy by converting tumor-supporting immune cells into tumor-fighting ones.
A new review examines how drugs that clear senescent cells could transform treatment of age-related cardiovascular disease.
A distinct immune remodeling process — separate from classical immunosenescence — predicts arterial stiffness with surprising accuracy.
CAR-M2 therapy successfully reversed kidney scarring in lab studies by eliminating harmful endothelial cells and promoting healing.
Novel liposome therapy delivers miR-10a to atherosclerotic plaques, reprogramming inflammatory macrophages and reducing disease progression in mice.
New research reveals how genetics, age, and herpesvirus infections create unique immune profiles that affect disease severity.
Researchers propose targeting lymph node entry mechanisms to improve immune tolerance in cardiac transplant recipients, potentially reducing rejection.
Dive deep into the molecular mechanisms of vascular aging and explore cutting-edge interventions — from senolytic therapies and nitric oxide restoration to exercise-induced remodeling and emerging pharmacological approaches — that are redefining what's possible in cardiovascular longevity.
Researchers created synthetic immune receptors that boost macrophages' ability to clear cellular debris, reducing inflammation in liver and heart disease.
A 2025 review maps the molecular drivers of cardiac aging and evaluates drugs, CRISPR, stem cells, and lifestyle as countermeasures.
New review reveals cancer vaccines work better alongside checkpoint inhibitors, offering hope for personalized treatment.
Researchers discovered specific cell markers that predict which leukemia patients will achieve lasting remission from CAR-T therapy.
A comprehensive review reveals how inflammaging—the fusion of aging and inflammation—fuels cardiovascular disease through senescence, mitochondrial dysfunction, and gut dysbiosis.
New study shows clearing senescent cells with Navitoclax improves heart function and reduces inflammation in heart failure with preserved ejection fraction.
New research reveals potential cancer risks following advanced CAR T-cell immunotherapy treatments.
A novel CTSL–Notch1–CUX1 pathway drives endothelial senescence and atherosclerotic plaque buildup, revealing fresh drug targets.
A single cardiovascular event creates inflammatory memory that drives chronic disease across multiple organs for years.
A landmark Circulation review reveals how aging blood vessels accelerate systemic decline — and outlines emerging therapies to stop it.
Researchers discover how cancer cells use metabolic enzyme PHGDH to evade immune detection, opening new combination therapy approaches.
Researchers created the first comprehensive atlas of bone metastases, revealing new immune therapy combinations that could help patients.
