20 articles
OSK gene therapy targeting engram neurons restored memory to youthful levels in aged mice and Alzheimer's models, reversing senescence hallmarks.
A comprehensive review reveals how immunosenescence and chronic neuroinflammation create a self-reinforcing cycle that accelerates dopaminergic neuron loss in Parkinson's disease.
IRISeq maps gene expression across aging mouse brains, finding lymphocytes fuel neuroinflammation and accelerate cellular aging.
Science-backed protocols using sunlight, UVB, and red light to boost testosterone, enhance immunity, and reverse age-related vision decline.
Cambridge researchers found a gene network that shuts off nerve repair โ and an existing hormone drug that reactivates it.
A deep mechanistic exploration of how hypothalamic IKKฮฒ/NF-ฮบB signaling, htNSC exosomal communication, and multi-axis hormonal dysregulation drive systemic aging โ plus cutting-edge therapeutic strategies.
Scientists discover adult brain cells keep epigenetic memories from development that may fuel gliomas but also enhance regeneration.
Scientists uncover the molecular mechanisms driving microglial aging in the brain, offering insights into neurodegeneration.
Large study reveals when patients with MOG antibody disease can discontinue immunosuppressive therapy without relapse.
A molecule called OLE restores microglia's protective function, reducing amyloid plaques and improving memory in animal models.
Stanford researcher reveals how proteins in young blood can rejuvenate aging brains and improve cognition.
New research reveals that the molecular state of immature neurons in the aged hippocampus predicts cognitive resilience โ not just their number.
A 9-day intranasal insulin regimen restored working memory, recognition memory, and reduced neuroinflammation in mice engineered to mimic hippocampal aging.
UCSF scientist reveals how engineered T-cells and CRISPR are transforming cancer treatment and prevention strategies.
New single-nucleus RNA sequencing reveals immature neurons persist in aged human hippocampus and may actively support cognitive resilience in Alzheimer's disease.
New research reveals how immune cytokines IL-4 and IL-13 directly signal to brain neurons to regulate synapses and cognitive function.
Breakthrough study shows complete reversal of severe Alzheimer's symptoms in mice, identifying new therapeutic targets for human treatment.
New research reveals that gene therapy for SMA causes significant immune activation, suggesting immune dysfunction is central to the disease.
New mouse research finds the trendy D+Q senolytic combo severely damages myelin, raising red flags for longevity self-experimenters.
Stanford researcher reveals how exercise, fasting, and sunlight trigger youthful blood proteins that rejuvenate aging organs.
