Inflammaging May Be a Western Phenomenon, Not a Universal Aging Hallmark
A major cross-population study finds that chronic inflammation linked to aging may reflect industrialized lifestyles, not biology alone.
20 articles
A major cross-population study finds that chronic inflammation linked to aging may reflect industrialized lifestyles, not biology alone.
Analysis of nearly 2,000 adults reveals systemic immune-inflammation index strongly correlates with epigenetic age acceleration.
New research reveals how chronic inflammation varies by person, paving the way for personalized interventions to combat age-related diseases.
Higher fibrinogen and immune activation scores in middle age strongly predicted who would develop frailty decades later.
New research links chronic low-grade inflammation to faster epigenetic aging, measured across four validated biological clocks.
A completed trial examines how a key inflammation pathway connects periodontitis stages to the chronic low-grade inflammation of aging.
New research reveals how low-grade inflammation creates a cycle of liver damage in older adults, pointing to promising therapeutic targets.
Study of 470 older adults reveals strong connection between periodontal inflammation and systemic inflammatory markers.
A simple ratio of platelets, neutrophils, and lymphocytes emerges as a versatile inflammation biomarker across major autoimmune diseases.
Research from sub-Saharan Africa shows urbanization dramatically alters inflammaging patterns, challenging universal aging models.
BioAge's oral NLRP3 inhibitor BGE-102 cut hsCRP by ~85% in weeks, signaling a potential breakthrough in treating chronic inflammation at scale.
BioAge's oral drug BGE-102 dramatically reduced hsCRP and IL-6 in obese participants with elevated inflammation, with a strong safety profile.
A comprehensive 2025 review maps the molecular and cellular mechanisms driving immune aging, from SASP to epigenetic drift.
Scientists identify blood biomarkers from aging immune cells that predict mobility, metabolism, and body composition changes in over 1,000 adults.
GlycanAge's Dubrovnik conference targets translating 25 years of inflammaging research into real clinical tools for doctors and patients.
A 452-person study maps how inflammaging biomarkers diverge by sex across age groups, revealing the biological roots of the sex-frailty paradox.
New research reveals kidneys actively fuel systemic inflammation during aging, offering targets for longevity interventions.
New research reveals how immune aging creates systemic inflammation that accelerates kidney disease, autoimmune conditions, and other age-related illnesses.
Machine learning analysis reveals STAT1 and three other biomarkers linked to accelerated immune aging in RA patients.
Greek researchers investigated whether whey protein can counter inflammation-driven muscle loss in older adults with chronic inflammation.