20 articles
A major cross-population study finds that chronic inflammation linked to aging may reflect industrialized lifestyles, not biology alone.
Analysis of nearly 2,000 adults reveals systemic immune-inflammation index strongly correlates with epigenetic age acceleration.
New research reveals how chronic inflammation varies by person, paving the way for personalized interventions to combat age-related diseases.
Higher fibrinogen and immune activation scores in middle age strongly predicted who would develop frailty decades later.
New research links chronic low-grade inflammation to faster epigenetic aging, measured across four validated biological clocks.
Mendelian randomization links circulating inflammatory proteins to retinal microvascular changes, heart disease risk, and lifespan — establishing causal direction.
A comprehensive review reveals how obesity and aging converge through shared inflammatory biomarkers, accelerating disease risk in the elderly.
A comprehensive review reveals how inflammaging—the fusion of aging and inflammation—fuels cardiovascular disease through senescence, mitochondrial dysfunction, and gut dysbiosis.
Discover how persistent low-grade inflammation drives the aging process and learn strategies to combat this silent threat to longevity.
Go beyond the basics to explore how complement pathways, regulatory failures, and senescent cells interact to drive the chronic inflammation that accelerates aging at the molecular level.
A completed trial examines how a key inflammation pathway connects periodontitis stages to the chronic low-grade inflammation of aging.
New research reveals how low-grade inflammation creates a cycle of liver damage in older adults, pointing to promising therapeutic targets.
Study of 470 older adults reveals strong connection between periodontal inflammation and systemic inflammatory markers.
Higher TNF-α levels at baseline increased injury risk by 25% per unit, while IL-1RA showed protective effects in runners.
A simple ratio of platelets, neutrophils, and lymphocytes emerges as a versatile inflammation biomarker across major autoimmune diseases.
Revolutionary framework combines quarterly biomarker testing with AI-powered lifestyle coaching to reduce aging-related inflammation.
Research from sub-Saharan Africa shows urbanization dramatically alters inflammaging patterns, challenging universal aging models.
BioAge's oral NLRP3 inhibitor BGE-102 cut hsCRP by ~85% in weeks, signaling a potential breakthrough in treating chronic inflammation at scale.
German study explored how lifelong inflammatory burden contributes to cardiac aging by measuring heart rate variability changes.
New research reveals how tissue fibroblasts orchestrate age-related inflammation, creating exhausted T cells that increase vulnerability to disease.
