Five Blood Biomarkers Link Frailty and Cognitive Decline in Aging Adults
New research identifies specific blood markers that independently predict both physical frailty and cognitive decline.
20 articles
New research identifies specific blood markers that independently predict both physical frailty and cognitive decline.
IRISeq maps gene expression across aging mouse brains, finding lymphocytes fuel neuroinflammation and accelerate cellular aging.
New research reveals how targeting brain inflammation could unlock novel therapeutic approaches for Alzheimer's disease.
New mouse study reveals aging causes region-specific neuroinflammation and perineuronal net accumulation linked to memory decline.
Study of 2,366 women shows biological aging markers predict future increases in tau, amyloid, and neuroinflammation proteins linked to dementia.
PET-MRI study of 54 cSVD patients links microglial activation to enlarged white matter perivascular spaces, not BBB leakage.
Multiomics study reveals gut microbiome shifts and inflammation markers detectable in earliest stages of cognitive decline.
A 4-protein panel in neuronal extracellular vesicles outperforms standard plasma tests in flagging early Alzheimer's brain changes.
New inflammatory markers could help doctors differentiate between methamphetamine-induced psychosis and schizophrenia using simple blood tests.
New research reveals how brain immune cells respond to vascular damage, offering clues for early Alzheimer's intervention strategies.
A comprehensive review reveals how immunosenescence and chronic neuroinflammation create a self-reinforcing cycle that accelerates dopaminergic neuron loss in Parkinson's disease.
A Framingham study of 2,844 adults links impaired endothelial function to higher Alzheimer's risk, brain shrinkage, and white matter damage.
Scientists uncover the molecular mechanisms driving microglial aging in the brain, offering insights into neurodegeneration.
New research reveals how GFAP protein actively shapes brain aging and could enable early detection of neurodegenerative diseases.
Research reveals concerning relapse patterns in primary central nervous system vasculitis, offering insights for better treatment timing.
New AI model using blood tests better predicts brain aging and amyloid buildup linked to dementia risk.
New research reveals persistent inflammatory brain lesions in pediatric MS patients, offering insights into early disease progression.
A comprehensive review examines how marine-derived bioactives like omega-3s, astaxanthin, and polysaccharides may combat chronic neuroinflammation underlying major neurodegenerative diseases.
Recent NIA findings spotlight lifestyle factors cutting Alzheimer's risk by 60%, calorie restriction slowing aging, and a gene regulating plaque toxicity.
Somatic mutations found in cancer driver genes accumulate in Alzheimer's brain macrophages, potentially driving the neuroinflammation that accelerates disease.