Fat-Regulating Protein HSL Has a Hidden Role That Rewrites Obesity Science
A key fat metabolism protein works inside cell nuclei to keep fat tissue healthy — its absence causes fat loss, not gain.
20 articles
A key fat metabolism protein works inside cell nuclei to keep fat tissue healthy — its absence causes fat loss, not gain.
A protein thought only to burn fat secretly protects fat cell health from inside the nucleus, reshaping obesity and metabolic disease research.
Reducing protein to recommended levels may double the longevity hormone FGF21, improving fat loss and insulin sensitivity within weeks.
FGF21 extends lifespan in animals by 30-40%. Here's what exercise and diet research reveals about boosting it naturally.
A Mass General Brigham trial found multivitamin users aged slower on 5 epigenetic clocks, with the biggest gains in those aging fastest.
University of Sydney researchers found that cutting fat or animal protein for just four weeks lowered biological age markers in older adults.
UCLA researchers eliminated senescent immune cells in mice, dramatically reversing liver damage even without diet changes.
A Cambridge review finds current protein guidelines target deficiency prevention, not optimal aging. Higher intake may protect strength and cognition.
A newly identified trigger in brown fat activates a hidden calorie-burning pathway and may unlock new treatments for bone disease.
University of Cologne researchers reveal how the amino acid leucine boosts cellular energy by preventing breakdown of critical mitochondrial proteins.
A proteomics study tracking 3,000 blood proteins reveals fasting's deepest benefits emerge only after 72 hours without food.
Disabling the MTCH2 protein in human cells supercharges fat burning and halts new fat cell growth — a potential obesity breakthrough.
A clinical trial found testosterone gel plus exercise prevented visceral fat increases in women over 65 recovering from hip fractures.
Japanese scientists engineered hybrid vitamin K molecules that are 3x more potent at regrowing neurons, potentially transforming Alzheimer's treatment.
Scientists mapped a two-pathway gut-brain alarm that shifts appetite from sugar to protein when essential amino acids drop.
NutritionFacts.org's most popular 2025 videos cover cancer growth prevention, NAD+ optimization, and evidence-based nutrition for longevity.
Scientists identify a new type of stem cell that activates with aging and supercharges belly fat production, opening anti-obesity targets.
New research suggests eating unprocessed meat could help people with Alzheimer's risk genes maintain better brain function.
New research reveals how hormone FGF21 activates brain circuits to boost metabolism and reverse obesity, offering alternative to GLP-1 drugs.
A daily tomato-soy juice rich in lycopene and isoflavones significantly reduced inflammatory proteins in adults with obesity after just four weeks.