20 articles
Scientists review breakthrough methods for transferring healthy mitochondria into damaged cells to restore cellular energy and combat aging.
Packaging mitochondria in erythrocyte-derived membranes dramatically improves delivery efficiency, pushing this experimental therapy closer to clinical reality.
Scientists isolate mitochondria-packed vesicles from healthy muscle tissue that transfer mitochondrial DNA to damaged cells, restoring energy metabolism.
Scientists packaged healthy mitochondria in red blood cell-derived vesicles, successfully restoring energy function in models of mitochondrial disease and Parkinson's.
A new protein-binder system precisely targets donor mitochondria to diseased cell types, reversing neurodegeneration in human and mouse models.
Engineered vesicles deliver healthy mitochondria to damaged brain vessels post-stroke, reprogramming metabolism and triggering angiogenesis in mice.
Researchers restored aging ovarian cell function by reactivating mitochondrial sharing via tunneling nanotubes, using FTY720 and 3D scaffolds.
A 2025 review reveals how damaged mitochondrial fragments drive brain inflammation while functional mitochondria transfer rescues injured neurons.
Scientists eliminated mitochondria from stem cells and embryos using enforced mitophagy, uncovering how mitochondrial DNA shapes development and species identity.
Scientists engineered macrophages with healthy donor mitochondria, dramatically improving their ability to repair heart tissue after myocardial infarction.
Tumor cells transfer mitochondria to normal fibroblasts through nanotubes, triggering cancer-associated fibroblast differentiation and fueling tumor growth.
A landmark editorial synthesizes how mitochondrial decline drives aging, neurodegeneration, and heart diseaseβand how new therapies may reverse it.
A mitochondrial-derived peptide dramatically improves muscle energy production and slashes oxidative stress β without adding more mitochondria.
A sweeping 2025 review maps how mitochondrial dysfunction fuels neurodegeneration, cancer, CVD, and aging β and what emerging therapies can do about it.
New review reveals how mitochondria coordinate metabolism by exchanging signals with other cellular compartments through specialized contact sites.
A Cambridge team discovered that boosting mitophagy via USP30 inhibition can clear harmful mtDNA mutations β opening a path to prevent mitochondrial disease.
Scientists develop LOCL-TL to map where proteins are made inside cells, discovering two distinct strategies for mitochondrial protein synthesis.
A comprehensive review of pathophysiology, genetics, and emerging therapies for mitochondrial myopathies, spotlighting elamipretide and gene therapy.
Scientists use red blood cells to transport healthy mitochondria into diseased brain cells, showing promise for treating Parkinson's.
A sweeping review maps every known strategy for delivering therapies directly to mitochondria, from lifestyle habits to nanocarriers and gene editing.
