Results for "Partial Epigenetic Reprogramming" in Cancer

20 articles

Nuclear Enzyme Breakthrough Reprograms Cancer Cells to Stop Growing
Cancer Research

Nuclear Enzyme Breakthrough Reprograms Cancer Cells to Stop Growing

Scientists discover how to reprogram cancer cells into harmless, non-dividing cells by targeting a nuclear enzyme pathway.

Research Paper
Mar 29, 2026 1
Genomic Instability at the Edge: Telomere Crisis, Epigenetic Drift, and Next-Generation DNA Repair Therapies
Cancer Research
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Genomic Instability at the Edge: Telomere Crisis, Epigenetic Drift, and Next-Generation DNA Repair Therapies

Dive deep into the molecular machinery of genomic instability — from telomere-driven crisis states and epigenetic remodeling at break sites to cutting-edge therapeutic strategies targeting DNA repair fidelity in aging and cancer.

TutorialAdvanced
May 2, 2026 0
Embryonic Cell States Found Driving Early Colorectal Cancer Spread
Cancer Research

Embryonic Cell States Found Driving Early Colorectal Cancer Spread

MIT researchers identify oncofetal cell states in colorectal tumors that mimic embryonic intestines and prime cancer cells for invasion.

Research Paper
Jun 12, 2026 0
How Cancer Cells Use Genome Doubling to Hide from Immune Attack
Cancer Research

How Cancer Cells Use Genome Doubling to Hide from Immune Attack

New research reveals that whole-genome doubling triggers epigenetic changes that silence antigen presentation, letting tumors evade CD8+ T cells.

Research Paper
Jun 12, 2026 0
New Histone Lactylation Sites Drive Breast Cancer Growth Through Metabolic Loop
Cancer Research

New Histone Lactylation Sites Drive Breast Cancer Growth Through Metabolic Loop

Scientists discover two new histone modifications that create a self-reinforcing cycle promoting breast cancer progression.

Research Paper
Apr 3, 2026 0
EMT Drives Cancer Spread Through a Spectrum of Reversible Cell States
Cancer Research

EMT Drives Cancer Spread Through a Spectrum of Reversible Cell States

A new review reveals how epithelial-to-mesenchymal transition fuels tumor invasion, immune evasion, and drug resistance through dynamic, reversible states.

Review
Apr 26, 2026 0
Engineered Tumor Switches Destroy Glioblastoma While Building Lasting Immunity
Cancer Research

Engineered Tumor Switches Destroy Glioblastoma While Building Lasting Immunity

Synthetic super-enhancers hijack glioblastoma's own regulatory circuits to trigger precise, tumor-only cell death and durable immune memory.

Research Paper
May 22, 2026 0
Scientists Map Cancer's Hidden RNA Switches That Control Cell Death and Growth
Cancer Research

Scientists Map Cancer's Hidden RNA Switches That Control Cell Death and Growth

New research reveals how chemical tags on RNA molecules drive cancer progression and could unlock targeted treatments.

Research Paper
Mar 28, 2026 0
Dormant Colorectal Cancer Cells Evade Chemo by Mimicking Embryonic Diapause
Cancer Research

Dormant Colorectal Cancer Cells Evade Chemo by Mimicking Embryonic Diapause

Cancer cells that downregulate SMC4 enter a low-proliferation, diapause-like state that resists standard chemotherapy, revealing a dangerous survival mechanism.

Research Paper
Jun 9, 2026 0
Scientists Identify Critical Window to Stop Cancer Before It Becomes Malignant
Cancer Research

Scientists Identify Critical Window to Stop Cancer Before It Becomes Malignant

New research reveals how progenitor cells drive the transition from benign to malignant cancer, offering potential intervention targets.

Research Paper
Apr 17, 2026 0
Scientists Discover How Cancer Cells Resist Chemotherapy Through Metabolic Reprogramming
Cancer Research

Scientists Discover How Cancer Cells Resist Chemotherapy Through Metabolic Reprogramming

New research reveals how nasopharyngeal cancer cells rewire their metabolism to survive chemotherapy, pointing to potential treatment strategies.

Research Paper
Mar 29, 2026 1
Cerebrospinal Fluid Analysis Reveals DNA Methylation Patterns in Pediatric Brain Tumors
Cancer Research

Cerebrospinal Fluid Analysis Reveals DNA Methylation Patterns in Pediatric Brain Tumors

New technique uses cerebrospinal fluid to decode methylation signatures in children's brain tumors, potentially improving diagnosis.

Research Paper
Apr 3, 2026 0
Blocking PID1 Reprograms Tumor Macrophages to Fight Cancer via Oxysterols
Cancer Research

Blocking PID1 Reprograms Tumor Macrophages to Fight Cancer via Oxysterols

Targeting a single protein in immune cells rewires cholesterol metabolism to flip immunosuppressive macrophages into tumor-fighting ones.

Research Paper
Jun 23, 2026 0
Scientists Find Enzyme That Triggers Cancer's Most Chaotic DNA Destruction
Cancer Research

Scientists Find Enzyme That Triggers Cancer's Most Chaotic DNA Destruction

Researchers identify N4BP2, the enzyme behind chromothripsis - a genetic catastrophe that helps one in four cancers rapidly evolve and resist treatment.

Press Release
Mar 29, 2026 1
SPP1+ Fibroblasts Drive Colorectal Cancer Liver Metastasis Through Metabolic Reprogramming
Cancer Research

SPP1+ Fibroblasts Drive Colorectal Cancer Liver Metastasis Through Metabolic Reprogramming

Spatial multi-omics reveals how specific fibroblasts create immunosuppressive environments that fuel colorectal cancer spread to the liver.

Research Paper
Mar 29, 2026 1
Human Cells Can Pass Damaged DNA Directly to Neighbors Through Nanotube Bridges
Cancer Research

Human Cells Can Pass Damaged DNA Directly to Neighbors Through Nanotube Bridges

A landmark Cell study reveals cells transfer cytoplasmic DNA fragments to neighbors via nanotubes, stably reshaping recipient genomes.

Research Paper
May 24, 2026 0
SIRT6 Protein Reverses Glioblastoma Drug Resistance Through Epigenetic Mechanism
Cancer Research

SIRT6 Protein Reverses Glioblastoma Drug Resistance Through Epigenetic Mechanism

Researchers discover how SIRT6 protein overcomes temozolomide resistance in deadly brain cancer by modifying histone lactylation patterns.

Research Paper
Apr 17, 2026 0
Histone Enzyme ASH1L Drives Cancer Spread to Bones Through Immune Cell Hijacking
Cancer Research

Histone Enzyme ASH1L Drives Cancer Spread to Bones Through Immune Cell Hijacking

New study reveals how cancer cells reprogram bone immune cells to fuel metastasis, offering potential therapeutic targets.

Research Paper
Apr 4, 2026 0
New Approach Reactivates Mutant p53 Tumor Suppressor in Cancer Patients
Cancer Research

New Approach Reactivates Mutant p53 Tumor Suppressor in Cancer Patients

Researchers develop selective method to restore function of mutated p53 protein, potentially offering new cancer treatment strategy.

Research Paper
Apr 5, 2026 0
Scientists Find Genetic Switch That Revives Exhausted Cancer Fighting T Cells
Cancer Research

Scientists Find Genetic Switch That Revives Exhausted Cancer Fighting T Cells

Researchers discovered how to restore tumor-killing power in worn-out immune cells by switching off just two genes.

Press Release
Mar 28, 2026 0
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