20 articles
New research reveals how a mother's methionine levels during pregnancy can influence her offspring's lifelong health through DNA modifications.
Go beyond antioxidant basics to explore how polyphenols hijack transcription factor networks, remodel chromatin, and what randomized trials actually show about aging biomarkers.
Dissect the molecular crosstalk between circadian oscillators and metabolic networks — from AMPK-CRY1 phosphorylation to tissue-specific clock uncoupling — and understand how to engineer your feeding window for maximum longevity benefit.
Go beyond the basics and explore the molecular machinery linking your circadian clock to metabolism — and why *when* you eat reshapes gene expression, insulin sensitivity, and cellular repair.
Early high-fat, high-sugar diets alter brain appetite circuits long-term, but probiotics and prebiotics may help undo the harm.
Small study reveals how exercise plus protein intake triggers beneficial gene changes in older women at metabolic risk.
New research reveals why muscle protein synthesis fails during calorie restriction, even with optimal protein intake.
New AI-discovered peptide mimics Ozempic's weight loss effects but targets only the brain's appetite center, avoiding nausea and muscle loss.
Scientists mapped a two-pathway gut-brain alarm that shifts appetite from sugar to protein when essential amino acids drop.
A proteomics study tracking 3,000 blood proteins reveals fasting's deepest benefits emerge only after 72 hours without food.
A new study finds intermittent fasting triggers coordinated changes in gut microbiome and brain regions controlling appetite and cravings.
Maternal supplementation with choline or betaine during pregnancy improves glucose control and weight management in offspring via gut bacteria.
Extended fasting activates powerful hormonal cascades, gut repair mechanisms, and epigenetic changes beyond typical intermittent fasting.
A key fat metabolism protein works inside cell nuclei to keep fat tissue healthy — its absence causes fat loss, not gain.
Experts say the next era of obesity care pairs GLP-1 medications with precision medicine, endoscopic procedures, and surgery for lasting results.
Disabling the MTCH2 protein in human cells supercharges fat burning and halts new fat cell growth — a potential obesity breakthrough.
University of Sydney researchers found that cutting fat or animal protein for just four weeks lowered biological age markers in older adults.
Stanford researchers found genetic variants in ~10% of people that blunt GLP-1 drug effectiveness, pointing toward precision diabetes care.
A 6-week RCT finds early TRE (8am–6pm) significantly improves insulin resistance, cholesterol, and weight in women with PCOS.
A protein thought only to burn fat secretly protects fat cell health from inside the nucleus, reshaping obesity and metabolic disease research.
