20 articles
A mechanistic deep dive into hormone replacement therapy evidence, growth hormone secretagogues, DHEA pharmacology, and cutting-edge endocrine reprogramming strategies — with clinical trial data and actionable protocols.
New research reveals how a master gene regulator controls FSH hormone production, potentially impacting fertility and aging.
Scientists discover membrane proteins that control progesterone signaling, potentially revolutionizing reproductive health and longevity.
New testing framework helps doctors quickly identify harmful mutations in PPARγ gene linked to rare fat disorders and cancer.
Adult-onset pseudohypoparathyroidism went undiagnosed until specialized genetic testing revealed the true cause of mysterious symptoms.
New trial explores whether short-term testosterone treatment creates lasting muscle benefits in older men through epigenetic memory.
A bile acid compound restores oocyte quality by activating a transcription factor that drives mitochondrial cleanup — offering a new target for fertility medicine.
Study finds prenatal exposure to common chemicals disrupts normal reproductive development in infants, especially girls.
Parental radiation exposure before conception disrupts mitochondrial DNA in offspring organs, affecting birth weight and development.
UCSF researchers show that enhancing autophagy in a small population of ovarian somatic cells restores egg production and delays aging.
Scientists develop innovative computational tool to better understand how nuclear receptors control metabolism and aging processes.
A new clinical review maps both established and emerging germline genes behind pituitary adenomas, reshaping how clinicians screen and counsel patients.
Study reveals how X-ray exposure during pregnancy affects mitochondrial DNA regulation across generations with lasting implications.
New sequencing technology identifies genetic diabetes forms in 17% of suspected cases, enabling personalized treatment approaches.
New research reveals how a key brain protein regulates stress hormones, body temperature, and fat storage in adults.
Scientists discover how lactate drives harmful inflammation after spinal injury and develop targeted therapy that restores function.
Scientists develop clinical decision tool to overcome cancer's adaptive resistance mechanisms through redox pathway targeting.
Researchers identify PANoptosis as a key mechanism in Alzheimer's, opening doors to novel therapeutic approaches.
A molecule from aged garlic activates a key longevity pathway in fat tissue, signaling the brain to restore muscle strength in old mice.
New research shows SIRT3 overexpression reverses AGE-induced senescence in human granulosa cells by restoring mitophagy and hormone output.
