20 articles
Study of 2,366 women shows biological aging markers predict future increases in tau, amyloid, and neuroinflammation proteins linked to dementia.
DNA methylation biomarkers from a simple blood test may track cognitive aging and neurological disease risk with unprecedented precision.
Stanford researchers found ribosome stalling in aging brain cells triggers faulty proteins and toxic clumps linked to Alzheimer's disease.
IRISeq maps gene expression across aging mouse brains, finding lymphocytes fuel neuroinflammation and accelerate cellular aging.
The SenNet atlas reveals where aging cells accumulate in human tissues, opening new doors for senolytic therapies and healthspan extension.
Boosting BNIP3 in muscle tissue extends fly lifespan and shields the brain from age-related degeneration via a muscle-brain signaling axis.
A deep mechanistic exploration of how hypothalamic IKKฮฒ/NF-ฮบB signaling, htNSC exosomal communication, and multi-axis hormonal dysregulation drive systemic aging โ plus cutting-edge therapeutic strategies.
Study of 833 people finds depression linked to premature biological aging in both brain structure and DNA methylation patterns.
Stanford researcher reveals how exercise, fasting, and sunlight trigger youthful blood proteins that rejuvenate aging organs.
Comprehensive review of 2021-2025 proteomics reveals 866 consensus protein changes and novel therapeutic targets in Alzheimer's disease.
Go beneath the surface to explore how NF-ฮบB signaling, IKKฮฒ activation, and hypothalamic stem cell decline drive whole-body aging โ and which interventions can slow the process.
Stanford researcher reveals how proteins in young blood can rejuvenate aging brains and improve cognition.
Dr. Sinclair explains the cellular mechanisms of aging and shares practical strategies to activate your body's natural longevity pathways.
A multi-omics analysis of over 1 million brain cells reveals how neurotransmitter systems change across aging and eight neuropsychiatric disorders.
New research identifies FTL1 protein as key driver of brain aging. Reducing it restored memory and neural connections in mice.
Declining Menin in the hypothalamus drives inflammation and aging. Restoring it reversed decline; D-serine amino acid improved cognition in mice.
27-Hydroxycholesterol triggers microglial senescence through iron dysregulation, and the iron chelator deferoxamine reverses the damage.
Deep inside your brain sits a tiny region that acts like a master control center for aging. Discover how the hypothalamus influences your lifespan โ and what you can do to keep it young.
New research identifies specific blood markers that independently predict both physical frailty and cognitive decline.
A landmark review argues neurodegeneration is driven by interacting misfolded proteins, not single culprits โ reshaping diagnosis and treatment.
