20 articles
Dissect the molecular crosstalk between circadian oscillators and metabolic networks — from AMPK-CRY1 phosphorylation to tissue-specific clock uncoupling — and understand how to engineer your feeding window for maximum longevity benefit.
A Mass General Brigham trial found multivitamin users aged slower on 5 epigenetic clocks, with the biggest gains in those aging fastest.
Go beyond the basics and explore the molecular machinery linking your circadian clock to metabolism — and why *when* you eat reshapes gene expression, insulin sensitivity, and cellular repair.
University of Sydney researchers found that cutting fat or animal protein for just four weeks lowered biological age markers in older adults.
Dr. Chris McGlory reveals how 5g daily omega-3 supplementation could help preserve muscle mass and strength in aging adults.
Six-month study compares intermittent fasting to calorie restriction for improving aging markers and metabolism.
Go beyond antioxidant basics to explore how polyphenols hijack transcription factor networks, remodel chromatin, and what randomized trials actually show about aging biomarkers.
A randomized trial finds that switching to high-carb or semi-vegetarian diets reduces biological age scores in adults aged 65–75 within just 4 weeks.
A dual-tracer study finds age-related differences in amino acid digestibility depend heavily on protein source, with sorghum most affected.
Dr. Valter Longo challenges the peptide and GLP-1 boom, arguing the full body of evidence points toward fasting, plant protein, and lower IGF-1.
UCLA researchers eliminated senescent immune cells in mice, dramatically reversing liver damage even without diet changes.
Hair graying and skin aging are metabolic problems driven by declining NAD+ levels, not just structural changes.
Essential vitamin D, omega-3, and magnesium insights plus vigorous exercise protocols that can reverse decades of aging.
Two-year study shows 25% calorie reduction creates organ-specific anti-aging effects, with cardiovascular and metabolic systems benefiting most.
A methionine-supplemented longevity diet outperformed Western and ketogenic diets by reducing frailty, fat mass, and insulin resistance while elevating GH, GLP-1, and FGF21.
Wake Forest researchers compared caloric restriction and time-restricted eating in 90 older adults over nine months.
New research reveals how targeting redox balance through lifestyle changes may simultaneously prevent heart disease, cancer, and neurodegeneration.
126-person study explores how tailored nutrition strategies with functional foods can prevent age-related diseases in older adults.
Study reveals older mice lose less muscle after nerve damage than younger ones, regardless of diet type.
Mayo Clinic study explores whether omega-3s can combat chronic inflammation and improve muscle function during exercise in aging adults.
