20 articles
Study of 2,366 women shows biological aging markers predict future increases in tau, amyloid, and neuroinflammation proteins linked to dementia.
Scientists discover 65 metabolites linked to sleep-wake cycles in older men, revealing new pathways between circadian health and aging.
DNA methylation biomarkers from a simple blood test may track cognitive aging and neurological disease risk with unprecedented precision.
Stanford researchers found ribosome stalling in aging brain cells triggers faulty proteins and toxic clumps linked to Alzheimer's disease.
Adults with stronger circadian rest-activity patterns show measurable signs of slower biological aging in blood-based biomarkers.
New research reveals how protein interactions and modifications control our 24-hour biological rhythms and disease risk.
IRISeq maps gene expression across aging mouse brains, finding lymphocytes fuel neuroinflammation and accelerate cellular aging.
The SenNet atlas reveals where aging cells accumulate in human tissues, opening new doors for senolytic therapies and healthspan extension.
Boosting BNIP3 in muscle tissue extends fly lifespan and shields the brain from age-related degeneration via a muscle-brain signaling axis.
A deep mechanistic exploration of how hypothalamic IKKฮฒ/NF-ฮบB signaling, htNSC exosomal communication, and multi-axis hormonal dysregulation drive systemic aging โ plus cutting-edge therapeutic strategies.
Explore the mechanistic changes in sleep architecture as we age โ from shrinking slow-wave sleep to disrupted circadian clocks โ and how these shifts cascade into hormonal, inflammatory, and metabolic dysfunction.
Scientists discover how daily rest-activity rhythms influence hundreds of metabolic compounds in older women's blood.
Study of 833 people finds depression linked to premature biological aging in both brain structure and DNA methylation patterns.
A landmark Nature study maps sleep duration against 23 biological aging clocks, revealing a U-shaped curve with an optimal window of 6.4โ7.8 hours.
Stanford researcher reveals how exercise, fasting, and sunlight trigger youthful blood proteins that rejuvenate aging organs.
Comprehensive review of 2021-2025 proteomics reveals 866 consensus protein changes and novel therapeutic targets in Alzheimer's disease.
Go beneath the surface to explore how NF-ฮบB signaling, IKKฮฒ activation, and hypothalamic stem cell decline drive whole-body aging โ and which interventions can slow the process.
Stanford researcher reveals how proteins in young blood can rejuvenate aging brains and improve cognition.
Dr. Sinclair explains the cellular mechanisms of aging and shares practical strategies to activate your body's natural longevity pathways.
A multi-omics analysis of over 1 million brain cells reveals how neurotransmitter systems change across aging and eight neuropsychiatric disorders.
