Single-Cell Atlas Reveals How 7 Million Cells Change as Mammals Age
Rockefeller scientists mapped epigenomic aging across 7M cells in 21 tissues, uncovering coordinated, program-like shifts that may unlock new therapies.
20 articles
Rockefeller scientists mapped epigenomic aging across 7M cells in 21 tissues, uncovering coordinated, program-like shifts that may unlock new therapies.
Massive cellular atlas shows aging starts earlier than expected and happens in sync across 21 organs, opening doors to targeted therapies.
Epigenetic clock pioneer Steve Horvath explains why the field is converging on validated biomarkers to make longevity medicine actionable.
A class of modified amino acids found in dog blood may unlock new ways to measure and track biological aging across species.
New research links chronic low-grade inflammation to faster epigenetic aging, measured across four validated biological clocks.
Stanford researchers found ribosome stalling in aging brain cells triggers faulty proteins and toxic clumps linked to Alzheimer's disease.
Adults with stronger circadian rest-activity patterns show measurable signs of slower biological aging in blood-based biomarkers.
Cells actively remodel their protein factories as we age, potentially triggering diseaseโbut this process could be targeted to slow aging.
An $80M family study, 37 proteins in centenarian blood, and a call to treat aging as a systems failure converge in new research.
New genetic and proteomic findings from centenarian studies uncover biological markers that distinguish the longest-lived humans from the rest of us.
Scientists boosted a protein that dampens chronic inflammation, and older mice grew stronger, more energetic, and had healthier bones.
New research reveals how a key dermal protein controls fast-cycling skin cells that maintain youthful skin integrity.
An $80M family study, 37 proteins in centenarian blood, and a call to rethink aging as a systems failure โ here's what's new.
A Nature Medicine study finds younger generations are biologically older than their parents at the same age, raising early-onset cancer risk by up to 57%.
Scientists discovered hundreds of unknown mini-proteins in failing hearts, potentially reshaping how we understand disease at the cellular level.
Popular at-home biological age tests promise to reveal your 'true' age, but experts question their accuracy and clinical value.
A new international conference in Cologne asks whether entropy โ the physics of disorder โ can unify aging science and point to measurable targets.
Recent NIH aging research highlights biological clocks in mice, calorie restriction effects, and olive oil's dementia protection benefits.
From a massive family study of centenarians to a paradigm shift in how aging is measured, longevity science is evolving fast.
A 20,000-person study finds IgG glycan patterns track biological aging, predict mortality, and shift toward youth with interventions.