57 articles
Celastrol outperforms leading senolytics by targeting the Hsc70-Bim protein complex, clearing zombie cells and reducing organ fibrosis in mice and flies.
China is increasing prestigious funding for early-career researchers. Will it reduce the intense competition stifling scientific innovation?
A new review reveals how aged hematopoietic stem cells disrupt immune balance and impair regeneration in brain, muscle, and skin.
Go deeper into the molecular machinery of neutrophil extracellular traps — how they form, what activates them with age, and why clearing them becomes increasingly difficult over time.
Senescent macrophages and cell death pathways fuel atherosclerosis — and new drug targets may finally interrupt the cycle.
From a 20% lifespan boost in mice to Alzheimer's glycosylation hallmarks, June's research roundup delivers dense longevity science.
A new review reveals how senescent healthy cells within tumors quietly drive cancer progression and therapy resistance.
Dasatinib + quercetin clears senescent kidney cells, restores anti-aging protein Klotho, and reverses transcriptional aging across multiple renal cell types.
A comprehensive 2025 review maps the mechanisms behind MSC senescence and surveys emerging rejuvenation strategies for cell-based therapies.
Spatial proteomics reveals how aging reshapes the gut's immune landscape — and points to metformin and senolytics as potential fixes.
Aging adipose tissue loses its ability to generate new fat cells, driving insulin resistance. New review maps the molecular culprits and best treatment options.
A sweeping review organizes 20 years of anti-aging pharmacology into three intervention axes and ranks the top compounds by research impact.
