Scientists Engineer Immune Cells to Hunt Cancer Using Metabolite Sensing Technology
Researchers modified NK and T cells with special receptors that help them track down and infiltrate solid tumors more effectively.
20 articles
Researchers modified NK and T cells with special receptors that help them track down and infiltrate solid tumors more effectively.
A mechanistic deep-dive into cutting-edge anti-inflammaging interventions — from senolytic pharmacology and precision cytokine targeting to partial reprogramming strategies that aim to restore youthful immune homeostasis.
New research reveals how metabolic molecules function as signaling agents that control immune responses within tumors.
Structural biology uncovers the exact amino acid motif causing species-specific drug failures, enabling transgenic mouse models for better P2X7 drug testing.
Advanced genetic analysis reveals new pathways to personalized RA therapy, addressing treatment failures in 30-40% of patients.
Cutting-edge genomic and immune profiling techniques uncover promising pathways for treating this chronic autoimmune condition.
Go beyond inflammaging basics to understand how aging reshapes immune cell populations, triggers the SASP, and locks the body into a state of chronic low-grade inflammation at the molecular level.
Latest advances in molecular diagnostics may revolutionize how clinicians detect and manage antibiotic-resistant gonorrhea infections.
A deep mechanistic exploration of neutrophil extracellular trap biology in the context of aging — from PAD4 citrullination dynamics and gasdermin-driven release to clinical immunopathology and next-generation therapeutic targets.
A new oligonucleotide probe workflow recovers complete RSV and norovirus genomes from low-titer clinical samples, transforming viral surveillance.
A published correction updates the April 2026 Aging Cell paper identifying a senescence-driven, immunomodulatory subtype of endometriosis.
Virtual patient replicas built from multimodal data may slash trial costs, generate synthetic control arms, and predict treatment response in IBD.
New research reveals atopic dermatitis has multiple biological subtypes, each requiring personalized treatment approaches.
Comprehensive review explores how combining genomics, proteomics, and metabolomics advances psoriasis understanding and treatment.
Researchers identify OGFRL1 gene deficiency as a novel cause of chronic bone disease, with promising treatment response to TNF inhibitors.
A massive viral gene library exposes hundreds of proteins that suppress immune detection — with major implications for infection, cancer, and aging.
Scientists discover tumor-associated immune cells can promote nerve growth and dramatically improve spinal cord injury recovery.
Demethyleneberberine, derived from traditional Chinese medicine, significantly reduced lung scarring by targeting NLRP3 inflammasome and EMT in mice.
Researchers discovered three molecular subtypes explaining why some lupus patients don't respond to standard treatments, opening doors to personalized therapy.
Go deeper into the molecular machinery of neutrophil extracellular traps — how they form, what activates them with age, and why clearing them becomes increasingly difficult over time.