20 articles
A comprehensive 2025 review charts the signaling pathways, drug targets, and emerging strategies scientists are using to slow human aging.
Dihydromyricetin, found in vine tea, acts as a dual senotherapeutic—suppressing SASP in fibroblasts and eliminating senescent microglia in Alzheimer's mice.
A landmark review reveals why aging immune systems lose the ability to clear senescent cells — and how new therapies could restore this critical defense.
RA patients show accelerated immune aging in T cells, B cells, and myeloid cells—predating joint inflammation and directly fueling autoimmunity.
Fucoidan, dasatinib+quercetin, and MitoQ each counteract hyperoxia-driven cellular senescence in fetal airway cells via distinct mechanisms.
A landmark 2025 review maps the molecular and cellular mechanisms driving immune aging, linking inflammaging to cancer, neurodegeneration, and infection.
A 2026 review evaluates how two common dietary flavonoids target senescent cells, potentially slowing aging and age-related disease.
A landmark review maps how senescent cells fuel gastrointestinal diseases—and why clearing them could transform treatment.
New review reveals how senescent brain cells fuel Alzheimer's progression and highlights promising senolytic therapies for cognitive protection.
Comprehensive review reveals how cellular senescence drives lung aging and disease, highlighting therapeutic potential of senolytics and senomorphics.
Scientists review promising therapies that eliminate or control senescent cells to promote healthier aging and prevent disease.
Researchers discover apigenin, found in fruits and vegetables, blocks harmful senescent cell activity and improves aging outcomes in mice.
New review reveals how senescent cells both prevent and fuel cancer, opening doors to precision therapies targeting aging pathways.
Comprehensive review reveals how drugs that eliminate or modify senescent cells could revolutionize anti-aging medicine.
Scientists identify cellular senescence as key driver of liver disease, opening doors to precision anti-aging treatments.
Review reveals how natural senotherapeutics like quercetin and resveratrol combat cellular aging in lungs to prevent respiratory decline.
New review reveals how targeting aging cells could break the vicious cycle between cellular senescence and metabolic dysfunction.
Researchers explore how eliminating senescent cells could revolutionize longevity medicine and healthy aging.
Revolutionary treatments targeting cellular aging could transform diabetic kidney disease care and prevent kidney failure.
Major analysis reveals how cellular senescence accelerates neurodegeneration and identifies promising therapeutic interventions.
