20 articles
Researchers identify mechanical modules that control how organisms develop different body shapes across 500 million years of evolution.
Comprehensive review reveals how drugs that eliminate or modify senescent cells could revolutionize anti-aging medicine.
Dissect the precise molecular architecture governing SASP regulation — from chromatin remodeling and cGAS-STING activation to extracellular vesicle-mediated spread and next-generation senolytic strategies.
Immorta Bio is using AI to move beyond disease treatment toward restoring youthful biology by clearing senescent cells and reviving stem cells.
Scientists decode how axolotl digits regrow, uncovering unique mechanisms that could revolutionize regenerative medicine.
Serif Biomedicines aims to create a new drug class combining mRNA and gene therapy benefits, targeting rare diseases and immune reprogramming.
A rigorous mechanistic deep-dive into the molecular logic of partial reprogramming — from chromatin dynamics and epigenetic clock reversal to in vivo delivery strategies, oncogenic risks, and the path to clinical translation.
A 6-month AI-driven personalized diet intervention cut BMI by 33% and reduced biological age by 8 years in morbidly obese patients.
Protuoso Biosciences raises $9.5M to build AI-engineered therapies that tackle multiple disease mechanisms simultaneously in one molecule.
Immorta Bio combines senolytics and stem cell revival with AI to achieve 70%+ lifespan extension in animal models.
A sweeping review details how longitudinal multi-omics data, AI, and systems biology are converging to create digital twins and transform healthcare.
A new review reveals senescent cells are far more heterogeneous than assumed, with major implications for senolytics and aging therapies.
C. elegans study finds all tested pro-longevity compounds extend male lifespan, but sulforaphane and metformin uniquely preserve late-life reproductive function.
Comprehensive comparison of Stereo-seq, Visium HD, CosMx, and Xenium platforms reveals key performance differences for cancer research applications.
Master the cutting-edge molecular targets, clinical trial data, and emerging therapeutic strategies aimed at reversing ECM aging — from senolytic combinations to biomaterial scaffolds and epigenetic reprogramming.
Go beyond the basics and explore the precise molecular mechanisms by which Yamanaka factors remodel the epigenome, silence cell identity, and unlock pluripotency — with implications for partial reprogramming therapies.
Revolutionary nanotechnology approaches demonstrate 30% better drug delivery and enhanced muscle regeneration in preclinical studies.
Researchers develop BH3 profiling to predict senolytic drug effectiveness, moving beyond one-size-fits-all aging treatments.
A deep mechanistic exploration of how hypothalamic IKKβ/NF-κB signaling, htNSC exosomal communication, and multi-axis hormonal dysregulation drive systemic aging — plus cutting-edge therapeutic strategies.
Advanced computational methods integrate genomics, metabolomics, and AI to accelerate discovery of bioactive compounds from natural sources.
