20 articles
Comprehensive comparison of Stereo-seq, Visium HD, CosMx, and Xenium platforms reveals key performance differences for cancer research applications.
A new machine learning tool called MaNeo scans tumor peptides to identify neoantigens that activate T cells against cancer while sparing healthy cells.
A novel cell-labeling tool reveals how ERα+ macrophages create immune-excluded niches in bone, blocking T cells from destroying cancer.
Scientists develop advanced drug delivery methods to detect and eliminate harmful senescent tumor cells that promote cancer spread.
New 3-D spatial mapping reveals four distinct immune-evasion niches in osteosarcoma that explain why checkpoint therapies fail.
A new review reveals how senescent healthy cells within tumors quietly drive cancer progression and therapy resistance.
A 13-modality molecular analysis of 173 AML patients reveals distinct subtypes, metabolic reprogramming, and a machine-learning-validated therapy target.
New review reveals key diagnostic features of superficial angiomyxoma, a rare benign tumor affecting middle-aged adults.
Scientists found drugs that kill senescent 'zombie cells' by blocking their key survival protein, shrinking tumors in mice.
New research reveals senescent cells have both harmful and protective roles, pushing anti-aging science toward targeted removal strategies.
A comprehensive review reveals how combining genomics, proteomics, and metabolomics is uncovering new AML targets and improving patient outcomes.
Research identifies genetic and environmental factors that may help predict who develops pancreatic neuroendocrine tumors and their outcomes.
Scientists discover how breast cancer builds deadly metastases using a 3D branching pattern, revealing new treatment targets.
Cambridge scientists engineer a nanoprobe that detects therapy-induced senescence non-invasively through a simple urine colorimetric test.
Researchers developed rat and mouse models mimicking early and middle stages of oral submucous fibrosis using bleomycin injections.
New review reveals how advanced genomics tools are revolutionizing cancer diagnosis and therapy development.
Cell Metabolism has published an erratum (correction notice) for a 2022 paper reporting that cancer cells co-opt nociceptive nerves to survive nutrient stress.
Researchers propose a unified model classifying cancer-associated fibroblasts by molecular phenotype and spatial location to guide precision therapy.
Researchers developed a new radiotracer that targets cancer cells more effectively when combined with mTOR inhibition therapy.
Stanford scientists used RFdiffusion and ProteinMPNN to build a compact α-helical TCR mimic with 9.5 nM affinity for a tumor antigen — and near-perfect peptide specificity.
