10 articles
Small molecule AA-20 clears protein aggregates and lipid droplets, extending C. elegans lifespan through a novel mTOR-independent autophagy pathway.
A landmark review reveals obesity and aging share molecular hallmarks that accelerate cardiovascular disease, and how anti-obesity drugs may reverse this.
A comprehensive review reveals how age-remodeled microenvironments cripple satellite cells, driving muscle loss—and how emerging therapies may reverse it.
A new partnership brings standardized spermidine into US clinical settings, shifting longevity science from shelves to physician-guided care.
Go beyond the basics to understand how your cells detect nutrient scarcity and orchestrate autophagy through mTORC1, AMPK, and lysosomal signaling — the molecular logic behind cellular self-renewal.
Go beyond the basics and explore the molecular machinery behind autophagy — from the three distinct recycling pathways to the key sensors that tell your cells when to clean house.
Comprehensive review reveals how cellular recycling process autophagy mediates benefits of diet, exercise, and longevity drugs across species.
New research reveals spermidine supplements and low-protein diets independently protect against brain aging in fruit flies.
Leading neuroscientist reveals how strategic stress through fasting and exercise triggers powerful anti-aging adaptations in the brain and body.
Comprehensive review reveals how immunosenescence creates tumor-promoting environments and reduces treatment effectiveness in elderly cancer patients.
