Gut Metabolite Imidazole Propionate Linked to Alzheimer's Progression
A bacterial gut metabolite worsens Alzheimer's pathology by damaging the blood-brain barrier and promoting tau tangles.
20 articles
A bacterial gut metabolite worsens Alzheimer's pathology by damaging the blood-brain barrier and promoting tau tangles.
Bacterial metabolite from flavonoids protects against graft-versus-host disease while preserving anti-cancer effects in stem cell transplants.
Clinical trial tests safety of combined prebiotic-probiotic supplement in 32 healthy participants over 5 months.
6-methoxykaempferol from sweet cherries restored immune function by 43% and improved beneficial gut bacteria in immunocompromised mice.
A microbiome metabolite depleted by antipsychotics protects synapses and cognition — and supplementing it may reverse the damage.
Vaginal microbiota applied to C-section newborns restores a key brain-signaling molecule on skin, improving early neurodevelopment.
New research reveals how a specific gut pathogen destroys enteric neurons in IBD patients and identifies a potential bacteriophage treatment.
New research reveals how gut microbiota-derived succinate exacerbates allergic airway inflammation by altering lung proteins.
Researchers discover unique RNA structures in bacteria that could inspire new approaches to cellular optimization and aging.
Engineered cerium-peptide microspheres show 76% reduction in IBD symptoms and 66% decrease in fibrosis markers in mouse studies.
New research shows electroacupuncture improves motor function and protects brain cells in Parkinson's disease through protein regulation.
New mouse research shows gut bacteria preserve egg supply via short-chain fatty acids, opening a dietary path to extended female fertility.
Study reveals how gut microbiota-derived propionic acid can restore reproductive function and reverse aging effects through gut-organ communication.
A novel gut microbiome metabolite chemically modifies liver proteins, impairing mitochondrial function and insulin signaling in obesity and fatty liver disease.
A mouse study shows CD38 inhibition protects colon architecture during 5-FU chemotherapy by preventing NAD+ depletion.
New research shows this beneficial gut microbe blocks obesity and improves metabolism through nicotinamide riboside production.
Research shows 8 prunes daily outperform medications and fiber supplements for constipation without side effects.
New research reveals how specific gut bacteria help the body absorb creatine, potentially offering a novel approach to depression treatment.
University study tests whether combining probiotics with prebiotics can restore healthy gut bacteria and immune function in people over 65.
Aging reduces beneficial gut bacteria that produce NDGA, a compound that prevents inflammatory bowel disease by blocking immune cell death.