20 articles
Oxford researchers tested whether spermidine could rejuvenate aging immune systems and improve vaccination effectiveness in adults over 65.
Novel KH-1 supplement containing spermidine and probiotics tested for autophagy stimulation and glucose control in 42 prediabetic participants.
DuoStim lets women with poor ovarian reserve collect more eggs in one cycle, potentially cutting time to a successful pregnancy.
Maastricht University investigated whether NA, NAM, and tryptophan together could restore mitochondrial function in physically compromised older adults.
Chinese researchers tested nucleotide supplements against aging markers in 122 participants over 4 months with promising early results.
A Phase 1/2 trial tests whether nicotinamide riboside can restore NAD+ balance and improve heart function in systolic HF patients.
A Phase IIa trial explores whether the HIF-PHI drug daprodustat can safely replace EPO injections in hemodialysis patients with anemia.
Italian researchers test plant-based compounds for brain health and quality of life in aging adults with promising early results.
A completed Nestlé-sponsored trial directly compared three popular NAD precursors head-to-head in healthy adults.
Study tested whether pimavanserin could prevent return of hallucinations and delusions in dementia patients who initially responded to treatment.
A Phase 2 pilot trial investigates whether the natural senolytic compound fisetin can reduce dysfunction and complications in COVID-19 patients.
First major clinical trial tests NMN supplement doses up to 900mg in middle-aged adults for anti-aging effects.
A Phase 1/2 trial tests whether dexmedetomidine can enhance the brain's glymphatic system to clear amyloid and tau during sleep.
A completed Mayo Clinic trial examined whether nicotinamide riboside can preserve bone density, muscle mass, and metabolic function in healthy older adults.
A completed trial investigates whether replenishing glutathione precursors can reverse metabolic dysfunction in elderly adults.
Small trial tests whether dasatinib plus quercetin can improve brain blood flow and cognition in at-risk older adults.
A completed pilot trial tests whether 2g/day of a novel carnosine formulation can restore neuromuscular function and quality of life in MS patients.
A phase II trial explores whether the amino acid L-arginine, with or without enzyme inhibitors, can improve erectile function and quality of life after prostate cancer radiation therapy.
Small trial explores how amiloride improves oxygen delivery to heart muscle by enhancing potassium transport in red blood cells.
A pilot RCT tests whether 3g daily citrulline malate improves mobility, strength, and biomarkers in women over 65 doing multicomponent training.
