Brain Health
Spermine Acts as Molecular Glue to Clear Alzheimer's and Parkinson's Proteins
New research reveals how spermine promotes protein condensation and autophagy to combat neurodegeneration in lab models.
Research Paper
Apr 10, 2026 0
Results for "Spermidine"
20 articles
Supplements
Spermidine Supplements Revive Immune Response to COVID Vaccines in Older Adults
A double-blind RCT finds daily spermidine supplementation reverses immune senescence markers and boosts vaccine antibody responses in adults over 65.
Research Paper
May 23, 2026 0
Longevity & Aging
Spermidine and Protein Restriction Fight Brain Aging Through Different Pathways
New research reveals spermidine supplements and low-protein diets independently protect against brain aging in fruit flies.
Research Paper
Apr 14, 2026 0
Supplements
Polyamines Could Be Key to Slowing Aging and Extending Healthspan
New research reveals how polyamine molecules regulate cellular aging and may offer promising anti-aging interventions.
Research Paper
Mar 29, 2026 2
Supplements
Urolithin A vs Spermidine: Which Longevity Compound Works Better for Cellular Health
New research reveals how these two popular longevity supplements target different cellular pathways for anti-aging benefits.
Research Paper
Mar 30, 2026 1
Longevity & Aging
PDRN Blocks Autophagy to Shield Key Anti-Aging Protein SIRT1 in Skin Cells
Salmon-derived PDRN prevents degradation of the longevity protein SIRT1 by reducing autophagy in UV- and oxidative stress-damaged skin cells.
Research Paper
May 6, 2026 0
Longevity & Aging
Salidroside Boosts Stem Cell Therapy to Reverse Premature Ovarian Failure
Combining the Rhodiola compound salidroside with mesenchymal stem cells restores ovarian function by blocking iron-driven cell death in a rat model.
Research Paper
Jun 25, 2026 0
Hormones
Nicotinamide Riboside Protects Egg Quality in Diabetic Mice
NAD+ precursor supplementation restored fertility markers and improved embryo development in diabetes-induced reproductive dysfunction.
Research Paper
Apr 4, 2026 0
Longevity & Aging
Plant Flavonoid DMY Clears Senescent Cells and Eases Alzheimer's in Mice
Dihydromyricetin, found in vine tea, acts as a dual senotherapeutic—suppressing SASP in fibroblasts and eliminating senescent microglia in Alzheimer's mice.
Research Paper
May 19, 2026 0
Supplements
PQQ Boosts Oocyte Quality by Cutting Oxidative Stress and Powering Mitochondria
Pyrroloquinoline quinone at 5 μM improved porcine oocyte maturation, reduced ROS, and raised blastocyst formation rates in a new lab study.
Research Paper
Apr 23, 2026 0
Longevity & Aging
PQQ Supplement Boosts Egg Quality and Fertility Through Mitochondrial Enhancement
New research shows pyrroloquinoline quinone improves egg maturation and embryo development in animal models.
Research Paper
Apr 4, 2026 0
Hormones
NMN Supplementation Improves Egg Quality in PCOS Mouse Model
Study shows nicotinamide mononucleotide (NMN) restores NAD+ levels and reverses declining oocyte quality in polycystic ovary syndrome.
Research Paper
Mar 29, 2026 14
Metabolic Health
Nanoplastics Accumulate in Mouse Testes and Trigger Sperm-Killing Ferroptosis via CISD1
50 nm polystyrene nanoplastics accumulate in mouse testes, degrading sperm quality and triggering iron-dependent cell death through a newly identified mitochondrial pathway.
Research Paper
Jun 20, 2026 0
Longevity & Aging
Blueberry Compound Delphinidin Reverses Microglial Aging to Fight Alzheimer's Pathology
Delphinidin, a natural anthocyanin, prevented microglial senescence via AMPK/SIRT1 signaling, reducing amyloid plaques and restoring cognition in AD mice.
Research Paper
May 17, 2026 0
Longevity & Aging
Pterostilbene Reverses Age-Related Fertility Decline in Mice Without Side Effects
Natural compound improves egg quality and pregnancy outcomes in aging mice, offering hope for age-related infertility treatment.
Research Paper
Apr 23, 2026 0
Longevity & Aging
Nano-Encapsulated Senolytic Cocktail Reverses Egg Cell Aging in Female Mice
Dasatinib and quercetin nanoparticles improve egg quality and fertility in aging mouse ovaries by clearing senescent cells.
Research Paper
Apr 2, 2026 0
Hormones
SIRT3 Blocks AGE-Driven Ovarian Aging by Boosting Mitophagy in Granulosa Cells
New research shows SIRT3 overexpression reverses AGE-induced senescence in human granulosa cells by restoring mitophagy and hormone output.
Research Paper
Jun 27, 2026 0
Supplements
NMN Supplements Slow Retinal Degeneration in Retinitis Pigmentosa Models
NAD+ decline drives mitochondrial dysfunction in retinitis pigmentosa. Oral NMN reversed retinal damage in rats via a newly identified metabolic pathway.
Research Paper
Jun 28, 2026 0
Longevity & Aging
NMN Supplementation Shows Promise for Improving Egg Quality in Animal Studies
Systematic review finds NMN enhances mitochondrial function and reduces oxidative stress in oocytes across multiple animal models.
Research Paper
Apr 3, 2026 0
Longevity & Aging
NAD+ Booster NMN Restores Egg Quality After Chemotherapy and Aging
NMN supplementation improved oocyte quality in mice with chemotherapy damage and older women, offering hope for fertility preservation.
Research Paper
Apr 6, 2026 0
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