20 articles
A new in vitro study shows Thymosin ฮฑ1 triggers dendritic cells to release IL-15, boosting CD8+ T cell killing and reducing HIV reservoir size.
New research reveals how aggressive T cell lymphomas exploit the same pathways that normally activate healthy immune responses.
A Phase 4 trial tests whether simplifying HIV treatment to two drugs worsens hidden viral replication and immune dysfunction.
Phase 1 trial examines whether vesatolimod can safely stimulate immune response in HIV controllers during treatment interruption.
Researchers identify how TSLP protein creates regulatory T cells that suppress immune responses in melanoma.
Researchers modified NK and T cells with special receptors that help them track down and infiltrate solid tumors more effectively.
New research reveals how SIRT2 regulates T cell responses, potentially improving cancer immunotherapy and immune function.
Pyruvate, a core metabolic molecule, suppresses interferon signaling by directly modifying STAT1 โ linking metabolism to immune control.
A runaway immune response โ not the pathogen itself โ drives citrus greening disease, echoing autoimmune mechanisms seen in human illness.
Groundbreaking study reveals how B cells acquire mutations in checkpoint genes to bypass immune tolerance in autoimmune thyroid disease.
New research reveals that mitochondrial energy pathways directly govern dendritic cell immune activation, with major implications for cancer and autoimmune therapies.
Scientists discover tumor-associated immune cells can promote nerve growth and dramatically improve spinal cord injury recovery.
RA patients with interstitial lung disease show accelerated cellular aging markers โ shorter telomeres and fewer mitochondrial DNA copies than RA patients without lung involvement.
A mechanistic deep-dive into cutting-edge anti-inflammaging interventions โ from senolytic pharmacology and precision cytokine targeting to partial reprogramming strategies that aim to restore youthful immune homeostasis.
Cancer immunotherapy drugs may enhance the body's natural healing processes by boosting regenerative immune responses.
A major review in Nature Medicine explores how CAR cell therapies may achieve deep immune 'reset' in autoimmune diseases by depleting pathogenic B cells.
Senescent T cells fuel psoriasis, eczema, and rosacea through toxic secretions. New therapies may finally break the cycle.
New research reveals how removing ZFP148 protein boosts CD8+ T cells' cancer-fighting ability and improves immunotherapy response.
Dying cancer cells release GPX4 protein that prevents immune system activation, revealing new immunotherapy targets.
New research reveals how immune cells use cysteine for both antioxidant defense and energy production, with major implications for cancer treatment.
