20 articles
Scientists propose integrated approach connecting cellular aging, gut bacteria, and tumor environment to improve cancer prevention and treatment.
A microbial enzyme from Bifidobacterium enhances anti-TNF therapy efficacy in IBD by reshaping immune regulation via histone lactylation.
Bacterial metabolite from flavonoids protects against graft-versus-host disease while preserving anti-cancer effects in stem cell transplants.
New research shows blocking PKM2 in immune cells promotes gut healing in colitis while preventing tumor formation.
New research reveals how gut microbes produce fatty acids that hijack cellular cleanup systems, leading to fat accumulation and immune dysfunction.
New research reveals how certain immune cells create alternative blood vessels that fuel pancreatic cancer growth and spread.
A primate single-nucleus study identifies NCoR1 decline as a conserved gut aging mechanism — and shows metformin can restore it.
A newly identified microRNA disrupts Paneth cell function in aging intestines, exposing older patients to life-threatening gut complications.
New research shows how a specific gut bacteria enhances anti-PD-1 therapy effectiveness in hard-to-treat colorectal cancers.
Researchers discover unique RNA structures in bacteria that could inspire new approaches to cellular optimization and aging.
A specific gut bacterium produces deoxycholic acid that hijacks tumor immunity, offering new targets for breast cancer treatment.
New review reveals how gut microbe chemicals directly reprogram tumor immune responses through multiple pathways.
New research reveals how specific gut bacteria can program neutrophils to become cancer-fighting allies in colorectal tumors.
Comprehensive review reveals how gut bacteria modify human gene expression through epigenetic mechanisms, opening new therapeutic avenues.
New research in Cell Metabolism explores how gut bacteria and their metabolites regulate immune checkpoint blockade efficacy in cancer patients.
New research reveals how skin microbes trigger severe immune reactions to cancer treatments, offering hope for prevention strategies.
Study reveals how IL-6 inflammation protein fuels liver cancer growth and identifies potential therapeutic vulnerability.
A newly discovered bacterial defense system depletes NAD+ in a way phages can't easily counter — revealing a deep evolutionary arms race.
A new review maps the bidirectional crosstalk between gut microbiota and cellular senescence driving multi-organ degeneration.
P. gingivalis bacteria secretes proteins that transform healthy cells into cancer-like cells, revealing new gut-cancer connections.
