Heart Health
Telomere Length Emerges as Key Biomarker for Heart Disease Risk
New review reveals how telomere shortening drives cardiovascular aging and identifies promising therapeutic targets for heart health.
Research Paper
Apr 10, 2026 0
Results for "Telomerase Activation" in Heart Disease
20 articles
Heart Health
Enzyme CTSL Triggers Rogue Notch1 Signaling That Drives Artery-Aging and Plaque
A novel CTSL–Notch1–CUX1 pathway drives endothelial senescence and atherosclerotic plaque buildup, revealing fresh drug targets.
Research Paper
May 30, 2026 0
Heart Health
TIE2 Receptor Circuit Drives Venous Malformation Growth Beyond PI3K Mutations
A feedforward ANGPT-TIE2 signaling loop amplifies PIK3CA-driven venous malformations, pointing to TIE2 inhibition as a more effective therapy than mTOR blockade.
Research Paper
May 22, 2026 0
Heart Health
Cancer Enzyme PHGDH Drives Immune Evasion Through Novel Non-Metabolic Pathway
Researchers discover how cancer cells use metabolic enzyme PHGDH to evade immune detection, opening new combination therapy approaches.
Research Paper
Mar 30, 2026 0
Heart Health
New Cancer Immunotherapy Combo Reprograms Immune Cells to Fight Tumors More Effectively
Scientists discover how to enhance cancer immunotherapy by converting tumor-supporting immune cells into tumor-fighting ones.
Research Paper
Mar 28, 2026 1
Heart Health
Scientists Discover HELZ2 Controls Fatty Liver and Atherosclerosis by Degrading ApoB mRNA
A forward genetic screen in mice reveals HELZ2 helicase degrades APOB mRNA, linking RNA stability to fatty liver disease and heart disease risk.
Research Paper
Jun 7, 2026 0
Heart Health
Scientists Engineer Super Macrophages That Clear Dead Cells to Fight Inflammation
Researchers created synthetic immune receptors that boost macrophages' ability to clear cellular debris, reducing inflammation in liver and heart disease.
Research Paper
Mar 29, 2026 3
Heart Health
Rare Cancer Gene Fusion Responds to Targeted Therapy Despite Unusual Structure
Scientists discover how an unusual gene fusion in melanoma still drives cancer growth and responds to targeted treatment.
Research Paper
Mar 28, 2026 1
Heart Health
Targeted Nanoparticles Reprogram Immune Cells to Reverse Atherosclerosis
Novel liposome therapy delivers miR-10a to atherosclerotic plaques, reprogramming inflammatory macrophages and reducing disease progression in mice.
Research Paper
Apr 2, 2026 0
Heart Health
CD40 Signaling Pathway Drives Heart Repair After Heart Attack
A specific CD40 signaling branch boosts macrophage cleanup of dead cells after MI, improving cardiac recovery in mice.
Research Paper
May 8, 2026 0
Heart Health
Mitochondrial Protein GTPBP3 Found Essential for Blood Vessel Growth and Ischemia Recovery
Deleting GTPBP3 in endothelial cells blocks angiogenesis via mtROS overload — and a mitochondria-targeted antioxidant reverses the damage.
Research Paper
May 20, 2026 0
Heart Health
Scientists Identify CAR-T Cell Markers That Predict Long-Term Cancer Remission
Researchers discovered specific cell markers that predict which leukemia patients will achieve lasting remission from CAR-T therapy.
Research Paper
Mar 29, 2026 3
Heart Health
Senolytics, Gene Therapy and Lifestyle Can Slow Cardiovascular Aging
A 2025 review maps the molecular drivers of cardiac aging and evaluates drugs, CRISPR, stem cells, and lifestyle as countermeasures.
Research Paper
May 11, 2026 0
Heart Health
Scientists Develop First Small-Molecule Activators for Heart-Protective PAK1 Kinase
Breakthrough discovery of PAK1 kinase activators shows promise for treating cardiac hypertrophy and heart failure through targeted enzyme enhancement.
Research Paper
Apr 3, 2026 0
Heart Health
SIRT5 Blocks Cardiac Fibrosis by Rewiring Fibroblast Metabolism
A sirtuin enzyme prevents heart scarring by keeping cardiac fibroblasts from switching to a pro-fibrotic metabolic state.
Research Paper
Apr 24, 2026 0
Heart Health
Plant Compound Tectorigenin Protects Heart from Hypertrophy by Stabilizing Mitochondria
Natural isoflavone prevents cardiac enlargement through novel mitochondrial protection pathway, offering new therapeutic approach.
Research Paper
Apr 3, 2026 0
Heart Health
SHMT2 Protein Drives Pulmonary Hypertension Via Newly Discovered Pathway
A mitochondrial enzyme found upregulated in pulmonary hypertension patients triggers vascular damage through a noncanonical mechanism — and a known drug can block it.
Research Paper
Jun 11, 2026 0
Heart Health
Single Protein PHF7 Repairs Hearts After Heart Attack by Converting Scar Tissue
Breakthrough study shows one epigenetic factor can transform cardiac fibroblasts into heart muscle cells, improving function after myocardial infarction.
Research Paper
Apr 3, 2026 0
Heart Health
Scientists Discover New Cancer Target That Could Transform Immunotherapy
Researchers mapped cancer surface proteins across 85 patient samples, identifying FAT2 as a promising target for CAR-T cell therapy.
Research Paper
Mar 29, 2026 3
Heart Health
Blocking a Liver Fat-Burning Gene Slashes LDL and ApoB Levels in Mice
Deleting CPT1a in mouse livers dramatically lowers ApoB-containing lipoproteins by accelerating clearance, revealing a new lipid metabolism target.
Research Paper
Jun 4, 2026 0
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