20 articles
A mechanistic deep-dive into cutting-edge anti-inflammaging interventions — from senolytic pharmacology and precision cytokine targeting to partial reprogramming strategies that aim to restore youthful immune homeostasis.
RA patients with interstitial lung disease show accelerated cellular aging markers — shorter telomeres and fewer mitochondrial DNA copies than RA patients without lung involvement.
A new in vitro study shows Thymosin α1 triggers dendritic cells to release IL-15, boosting CD8+ T cell killing and reducing HIV reservoir size.
Stanford researchers used modified immune proteins to enhance neurogenesis and cognitive function in aged mouse brains.
Master the molecular architecture of complement dysregulation in aging — from regulatory protein biochemistry to cutting-edge therapeutic targets — and understand how precision interventions can restore balance without dismantling immunity.
Cancer immunotherapy drugs may enhance the body's natural healing processes by boosting regenerative immune responses.
Scientists identify key mechanism that determines why some immune thrombocytopenia patients maintain remission after stopping treatment.
Revolutionary precision immunotherapies use AI and cellular engineering to target lupus at its source, offering hope for durable remission.
Targeting immune diseases before symptoms appear can delay clinical onset by over two years, offering new prevention strategies.
New cell-based treatments including CAR-T therapy could transform outcomes for systemic sclerosis patients.
BNT162b2 mRNA vaccine induces special immune cells that protect against severe illness and may slow aging-related decline.
A major review in Nature Medicine explores how CAR cell therapies may achieve deep immune 'reset' in autoimmune diseases by depleting pathogenic B cells.
Phase 1 trial examines whether vesatolimod can safely stimulate immune response in HIV controllers during treatment interruption.
A Phase 4 trial tests whether simplifying HIV treatment to two drugs worsens hidden viral replication and immune dysfunction.
A completed trial tests whether diode laser treatment reduces TLR-4 in saliva, linking periodontal inflammation to systemic aging biology.
Breakthrough study shows CAR T-cell therapy normalizes neutrophil function in lupus, offering new hope for autoimmune treatment.
A 2025 meta-analysis of 11 RCTs finds Tα1 reduces 28-day sepsis mortality overall, but high-quality trial data tells a more nuanced story.
Senescent cells drive cyst growth in ADPKD, and targeting them with senolytics or the aldose reductase inhibitor epalrestat delays disease progression.
New targeted therapies and biomarker-driven approaches are revolutionizing RA management, potentially improving healthspan for millions.
Senescent T cells fuel psoriasis, eczema, and rosacea through toxic secretions. New therapies may finally break the cycle.
