Metabolic Health
SGLT2 Inhibitors May Slow Aging by Clearing Senescent Cells
Diabetes drugs like empagliflozin show surprising anti-aging effects — mimicking caloric restriction and reducing senescent cell burden.
Research Paper
May 15, 2026 0
Results for "Telomere Interventions" in Diabetes
20 articles
Metabolic Health
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Sirtuins: Your Body's Longevity Enzymes and How to Activate Them
Discover how sirtuins act as your cellular repair crew and learn practical ways to boost these powerful longevity proteins naturally.
TutorialBeginner
Apr 11, 2026 0
Metabolic Health
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Sirtuins: The NAD+-Powered Guardians of Cellular Longevity
Explore how sirtuins use NAD+ as a molecular switch to regulate aging, DNA repair, and metabolism — and what happens when this system breaks down.
TutorialIntermediate
May 2, 2026 0
Metabolic Health
Triple Therapy Targets Diabetes and Muscle Loss in Elderly Adults
Mediterranean diet, resistance training, and diabetes medication combined to combat sarcopenia and improve metabolic health in older adults.
Clinical Trial
Mar 28, 2026 1
Metabolic Health
AI-Powered Nutrigenetics Slashes BMI and Reverses Biological Aging in Morbid Obesity
A 6-month AI-driven personalized diet intervention cut BMI by 33% and reduced biological age by 8 years in morbidly obese patients.
Research Paper
May 21, 2026 0
Metabolic Health
Can Two Weeks of Exercise Restore Mitochondrial Quality Control? (Trial Registration)
A completed OSU trial investigates whether short-term exercise training can restore impaired mitochondrial cleanup pathways in overweight and obese skeletal muscle.
Clinical Trial
Jun 15, 2026 0
Metabolic Health
NAD Precursor Combo Tested to Boost Muscle Mitochondria in Elderly Adults
Maastricht University investigated whether NA, NAM, and tryptophan together could restore mitochondrial function in physically compromised older adults.
Clinical Trial
May 8, 2026 0
Metabolic Health
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Insulin Resistance Decoded: Ectopic Lipids, Mitochondrial Failure, and the mTOR-IRS Axis
A deep mechanistic exploration of how ectopic lipid accumulation, mitochondrial dysfunction, mTOR-IRS1 feedback, and inflammatory crosstalk converge to drive age-related insulin resistance — plus emerging therapeutic strategies.
TutorialAdvanced
May 2, 2026 0
Metabolic Health
NIH Funds Pancreas Atlas and Heart Risk Models Targeting Age-Related Disease
Three NIH-funded studies this week tackle metabolic decline, cardiac risk, and brain tumors — all with aging implications.
Press Release
May 13, 2026 0
Metabolic Health
Deleting HDAC9 Gene Slows Fat Tissue Aging and Boosts Mitochondrial Function in Mice
Mice lacking the HDAC9 gene gained less fat with age, accumulated fewer senescent cells, and showed improved mitochondrial respiration in adipose tissue.
Research Paper
Apr 27, 2026 0
Metabolic Health
Metformin Shows Promise for Healthy Aging in Non-Diabetic Adults
Wake Forest study explores whether the diabetes drug metformin can trigger cellular changes linked to longevity in healthy people.
Clinical Trial
Mar 28, 2026 1
Metabolic Health
Scientists Map How Cholesterol Controls Cell Growth Through mTOR Pathway
New cryo-EM structures reveal how LYCHOS protein senses cholesterol levels to regulate mTORC1 signaling, offering drug targets for aging.
Research Paper
Apr 5, 2026 0
Metabolic Health
Nutritional Intervention Shows Promise for Type 2 Diabetes Management
84-person study reveals how targeted nutrition counseling impacts blood sugar, weight, and heart health in diabetic patients.
Clinical Trial
Mar 28, 2026 0
Metabolic Health
NIH Spotlights Pancreatic Aging, Heart Risk and Testosterone in Cancer Defense
Three new NIH-funded findings tackle metabolic aging, cardiovascular risk, and a surprising hormonal brake on brain tumors.
Press Release
May 14, 2026 0
Metabolic Health
mTOR Inhibition Triggers Hidden Lipid Survival Pathways That Fuel Cancer Growth
Blocking mTOR forces cancer cells to rewire cholesterol uptake and transport, revealing new drug targets when combined with rapamycin.
Research Paper
May 22, 2026 0
Metabolic Health
Exercise Prevents Chronic Disease Through Direct Biological Mechanisms
New research reveals how regular physical activity directly prevents and slows progression of major age-related diseases.
Research Paper
Mar 28, 2026 1
Metabolic Health
Magnesium Controls Cellular Energy and May Slow the Pace of Aging
A new review reframes magnesium as a master regulator of mitochondrial energy, metabolic disease, and biological aging.
Review
Jun 6, 2026 0
Metabolic Health
GLP-1 Receptor Agonists Show Promise for Longevity and Metabolic Health
New England Journal review explores the expanding therapeutic potential of GLP-1 drugs beyond diabetes treatment.
Research Paper
Apr 9, 2026 0
Metabolic Health
Metformin Shows Promise for Preventing Frailty in Older Adults
Major trial tests whether diabetes drug metformin can prevent frailty syndrome that affects millions of aging adults.
Clinical Trial
Mar 28, 2026 1
Metabolic Health
Intensive Lifestyle Changes Can Reverse Prediabetes Regardless of Race
Major study shows lifestyle intervention effectively reverses prediabetes in both African American and Caucasian participants with family diabetes history.
Clinical Trial
Mar 28, 2026 2
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